Caister Academic Press

Pathogenic Fungi: Structural Biology and Taxonomy

Publisher: Caister Academic Press
Edited by: Gioconda San-Blas and Richard A. Calderone
Instituto Venezolano de Investigaciones Científicas, Caracas, Venezuela and Georgetown University, Washington DC, USA
Pages: viii + 372
Publication date: June 2004
ISBN: 978-0-9542464-7-1
Price: GB £219 or US $250Buy book
Publication date: June 2004
ISBN: 978-1-913652-47-0
Price: US $319Buy ebook
Pathogenic Fungi book
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During the past decade we have witnessed a mushrooming of papers in the area of medical mycology; detailing major advances in areas such as genomics, molecular and cellular biology, molecular epidemiology, immune response and vaccine development, and strategies to combat infections in humans. This sheer volume of information makes it extremely difficult for the busy research scientist and/or teacher of medical mycology to keep abreast of all the latest advances. This book, together with its companion volume Pathogenic Fungi: Host Interactions and Emerging Strategies for Control, brings together expert international authors who critically review current topics, and through the provision of extensive reference sections positively encourage readers to pursue the subject in greater detail.

The book is divided into two sections: Fungal Dimorphism and Pathogenicity and New Taxonomic Tools. The first section focuses on morphogenesis, the cell cycle, and the cell wall of human pathogens. These play a major role in elucidating fungal relationships, both with the environment and with the host. Experts in fungal structural biology contribute in-depth reviews on a variety of topics with a focus on molecular and biochemical analysis. The final chapter in this section presents a fascinating review of how mathematical modelling can be used to understand the building of three-dimensional cell structures in the morphogenetic process. The second section, entitled New Taxonomic Tools, presents novel approaches to aid the understanding of strain variability, the significance of environmental and patient strains, and the relatedness of uncultured; fungi. In addition the use of molecular tools for the taxonomic classification of previously unclassifiable fungi is featured.

Essential reading for everyone with an interest in medical mycology including: mycologists, biotechnologists, molecular biologists, and pharmaceutical and biotechnology companies.


"Each chapter of this book is a critical review of current knowledge on the topic in question, with an extensive bibliography" from CAB International (2004).

"These two companion books have brought together an international group of authors who have provided comprehensive reviews of the current understanding about pathogenic fungi ... They will be important additions to departmental and institutional libraries" from Microbiology Today (2005).

"From the outset let it be stated clearly, unambiguously and emphatically: these are two truly excellent books; the best in the field I have seen in many years. There is not a single weak chapter to be found in either volume. The writing is first class, and the authors provide thought-provoking, critical ideas as well as up-to-date, very comprehensive coverage of their topics." from Mycological Research (2005) 109: 126-127.

"... essential and inspiring reading." from Mycological Research (2005) 109: 126-127.

"... an important interpretation of recent literature, a valuable addition to collections, and recommended reading for investigators seeking a broad appreciation for the current state-of-the-art." from Emerging Infectious Diseases (2005) 11: 643.

"highly recommended" from Aus. J. Med. Sci. (2006) 27(3) 122-123.

Table of contents
1. The Structure and Composition of the Fungal Cell Wall
Rafael Sentandreu, M. Victoria Elorza, Eulogio Valentín, and José Ruiz Herrera
2. Biosynthesis of the Fungal Cell Wall
José Ruiz-Herrera, M. Victoria Elorza, Peggy E. Alvarez, and Rafael Sentandreu
3. Cell Cycle of Fungal Pathogens
J. Berman and Neil A. Gow
4. Morphogenesis in Candida albicans
Tamaki Cho
5. Morphogenesis in Other Agents of Systemic Mycoses
Gioconda San-Blas and Gustavo Niño-Vega
6. Regulation of Morphogenesis by Conserved Developmental Pathways in Pathogenic Fungi
Idit Hazan and Haoping Liu
7. Beyond Molecular Biology: Fungal Morphology as a Mathematical, Biophysical and Computational Subject
Gioconda San-Blas and Juan Murgich
8. The Use of Phylogenetic Analysis to Investigate Uncultured Microbes In Medical Mycology
Leonel Mendoza and Víctor Silva
9. Gene Genealogical Analyses of Human Fungal Pathogens
Jianping Xu
10. Polysaccharides F1SS: Taxonomic and Evolutionary Characters for Ascomycetes
A. Prieto, O. Ahrazem, M. Bernabé and J.A. Leal

How to buy this book

(EAN: 9780954246471 9781913652470 Subjects: [microbiology] [medical microbiology] [molecular microbiology] [mycology] )