Caister Academic Press

Acanthamoeba: Biology and Pathogenesis

Author: Naveed Khan
Published: 2009   ISBN: 978-1-904455-43-1
Everything that is known about Acanthamoeba is critically reviewed and divided into easy-to-follow sections. The current state of research on genomics, molecular and cellular biology, life cycles, geographical distribution, role in ecosystem, morphology, motility, phylogenetics, genotyping, metabolism, regulation of morphogenesis, host-parasite interactions, the molecular and immunological basis of pathogenesis, methods of transmission, epidemiology, clinical manifestation, diagnosis, treatment, new target development and drug resistance, and much more. read more ...

Figure from: Acanthamoeba Biology and Pathogenesis

Full details of this book at Acanthamoeba. More figures at Acanthamoeba Figures.

Acanthamoeba

Acanthamoeba

Section D. Figure 4. A and B. Anatomy and the cellular structures of the microvessels of the human brain tissue; C. in vitro cultures of brain microvascular endothelial cells. Note that in vitro cultures are positive for factor VIII, carbonic anhydrase IV, uptake of fluorescently labelled acetylated low density lipoprotein, and gamma-glutamyl transpeptidase indicating their brain endothelial origin; and D. Ex vivo model of the blood-brain barrier. Transwells can be used to grow brain microvascular endothelial cells into the upper chamber on a permeable support, and astrocytes can be cultured into the bottom chamber.

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