Acanthamoeba: Biology and Pathogenesis
Author: Naveed Khan Published: 2009 ISBN: 978-1-904455-43-1 Everything that is known about Acanthamoeba is critically reviewed and divided into easy-to-follow sections. The current state of research on genomics, molecular and cellular biology, life cycles, geographical distribution, role in ecosystem, morphology, motility, phylogenetics, genotyping, metabolism, regulation of morphogenesis, host-parasite interactions, the molecular and immunological basis of pathogenesis, methods of transmission, epidemiology, clinical manifestation, diagnosis, treatment, new target development and drug resistance, and much more. read more ... |
Figure from: Acanthamoeba Biology and Pathogenesis
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Section D. Figure 14. Diagrammatic representation of Rho activation leading to the blood-brain barrier permeability changes. RhoA activation induces myosin light-chain phosphorylation (P-MLC) via Rho kinase causing redistribution/alteration of tight junction proteins, zonula occludens-1 (ZO-1) and occludin, resulting in the elevation of barrier permeability.
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