Acanthamoeba: Biology and Pathogenesis
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Author: Naveed Khan Published: 2009 ISBN: 978-1-904455-43-1 Everything that is known about Acanthamoeba is critically reviewed and divided into easy-to-follow sections. The current state of research on genomics, molecular and cellular biology, life cycles, geographical distribution, role in ecosystem, morphology, motility, phylogenetics, genotyping, metabolism, regulation of morphogenesis, host-parasite interactions, the molecular and immunological basis of pathogenesis, methods of transmission, epidemiology, clinical manifestation, diagnosis, treatment, new target development and drug resistance, and much more. read more ... |
Figure from: Acanthamoeba Biology and Pathogenesis
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Section C. Figure 5. Indirect immunofluorescence assays. Serum or mucosal secretions from a suspected patient is incubated with pathogen (e.g., Acanthamoeba)-coated slides, at various titres. A strong reaction suggests Acanthamoeba as the causative agent. Note that the levels of anti-Acanthamoeba antibodies in normal populations may be in the range of 1:20 to 1:60, however, patients with severely impaired immune system may not develop a high titre, thus other clinical findings should be taken into account for the correct diagnosis.
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