Caister Academic Press

Dynamics of Microbes in the Natural Setting: Development of the Geochip

Joy D. Van Nostrand, Zhili He and Jizhong Zhou
from: Environmental Microbiology: Current Technology and Water Applications (Edited by: Keya Sen and Nicholas J. Ashbolt). Caister Academic Press, U.K. (2011)


This chapter provides an overview of various microarrays available for environmental analysis, and building on previous chapters of this book, has the primary focus of describing functional gene arrays (FGAs). While many FGAs have been designed, the most comprehensive FGA available to date is the GeoChip, which targets thousands of key functional genes involved in the geochemical cycling of carbon (C), nitrogen (N), phosphorus (P), and sulphur (S), metal resistance and reduction, energy processing and contaminant degradation. Many studies have been performed using the GeoChip, showing it to be a powerful tool for rapid, sensitive and specific examination of microbial communities in a high-throughput manner. As such, the GeoChip is well-suited for linking geochemical processes with microbial community function and structure. However, challenges still remain with the use of FGAs and other microarrays for microbial community analysis, which one day may aid in revolutionizing how we assess microbial water quality read more ...
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