Genetics of O-antigens, Capsules, and the Rugose Variant of Vibrio cholerae
from: Vibrio cholerae: Genomics and Molecular Biology (Edited by: Shah M. Faruque and G. Balakrish Nair). Caister Academic Press, U.K. (2008)
The human pathogen Vibrio cholerae produces three major cell-surface associated polysaccharides, including (i) lipopolysaccharide (LPS), (ii) capsule, and (iii) rugose exopolysaccharide. While LPS and capsule primarily help the bacterium to evade host defense mechanisms, the rugose exopolysaccharide may aid the bacterium in persisting in the nutrient-deficient aquatic environments. This chapter describes underlying genetic elements and mechanism(s) involved in the biosynthesis and regulation of LPS, capsule and rugose exopolysaccharide elicited by V. cholerae read more ...