Genetics of Vibrio cholerae Colonization and Motility
Brooke A. Jude and Ronald K. Taylor
from: Vibrio cholerae: Genomics and Molecular Biology (Edited by: Shah M. Faruque and G. Balakrish Nair). Caister Academic Press, U.K. (2008)
Survival of Vibrio cholerae either in the aquatic environment or in the human host is mediated by appropriate expression of factors that control motility, colonization, production of virulence factors, as well as sensing the cell density (quorum sensing). Successful transition of the organism between the aquatic and the host intestinal environments thus depends on the coordinated activity of a number of genes and regulatory circuits. Recent developments in our understanding of the complex gene regulation supporting the cyclic transitions and the dual lifestyle of V. cholerae has been presented and discussed read more ...