Veterinary Vaccines with a Focus on Bovine Mastitis
John R. Middleton
from: Vaccine Design: Innovative Approaches and Novel Strategies (Edited by: Rino Rappuoli and Fabio Bagnoli). Caister Academic Press, U.K. (2011)
Abstract
While novel approaches to vaccination against diseases of veterinary importance are being explored, currently marketed products, in general, employ old technology with the majority of products still being killed, modified live, or toxoid preparations. Due to the breadth of diseases encountered in veterinary medicine and the large number of vaccines marketed and under development, this chapter will focus on vaccines aimed at preventing bovine mastitis with a particular focus on Staphylococcus aureus, a bacterium that not only causes mastitis in cattle, but is a leading cause human infection. Vaccine developments for S. aureus in cattle will be compared with research aimed at preventing staphylococcal infection in humans. The remainder of the chapter will discuss other available vaccines aimed at preventing bovine mastitis and serve to illustrate that the goals of vaccination may differ depending on the type of infection being prevented read more ...
