Dynamics and Robustness of Metabolic Networks: a Systems Biology Review of Escherichia coli Metabolism
Eivind Almaas, Per Bruheim, Rahmi Lale and Svein Valla
from: Systems Microbiology: Current Topics and Applications (Edited by: Brian D. Robertson and Brendan W. Wren). Caister Academic Press, U.K. (2012)
Abstract
The functional repertoire of an organism's metabolic network is closely linked to its phenotype and potential for utility in metabolic engineering applications. In this chapter, we discuss a systems biology view of Escherichia coli metabolism by integrating current genome-scale computational modelling approaches with available molecular genetics tools, as well as the experimental framework for metabolite and metabolic flux determination read more ...
