Caister Academic Press

Physiological Proteomics of Staphylococcus aureus: From the Protein Inventory to Stress Physiology and In Vivo adaptation

Susanne Engelmann, Stephan Fuchs and Michael Hecker
from: Staphylococcus: Genetics and Physiology (Edited by: Greg A. Somerville). Caister Academic Press, U.K. (2016) Pages: 119-132.


Here we present the different facets of proteomics turning it into a valuable tool for a more comprehensive understanding of metabolism and stress and starvation responses of Staphylococcus aureus. Relying on a combination of gel-based and gel-free proteomics procedures, new fields in staphylococci physiology such as phosphoproteomics, protein damage or proteolysis on a proteome wide scale are addressed. Finally, we show that stress/starvation proteomics signature libraries are essential diagnostic tools for the analysis of the physiological state of S. aureus cells under both in vitro and in vivo conditions read more ...
Access full text
Related articles ...