Bioinformatics Challenges in Targeted Proteomics
Lars Gustav Malmström
from: Proteomics: Targeted Technology, Innovations and Applications (Edited by: Manuel Fuentes and Joshua LaBaer). Caister Academic Press, U.K. (2014)
Targeted proteomics is becoming an important technology since it is capable of producing quantitative data with high reproducibility and accuracy for several proteins in a single experiment. The user needs to specify in great detail what to measure and the produced data is analyzed using techniques that have been specially developed for this technology. Targeted proteomics is therefore fundamentally dependent on an extensive set of software tools at almost every step. This chapter describes the bioinformatics challenges in targeted proteomics and suggests possible tools which can be used in each step read more ...