Pharmaceutical Aspects of Probiotics and Prebiotics
Indu Pal Kaur, Parneet Kaur Deol, Simarjot Kaur Sandhu and Parveen Rishi
from: Probiotics and Prebiotics: Current Research and Future Trends (Edited by: Koen Venema and Ana Paula do Carmo). Caister Academic Press, U.K. (2015) Pages: 469-486.
In recent times, increasing evidence of benefits of probiotics, for health restoration coupled with consumer's inclination towards safe, natural, and cost effective substitutes for drugs, has generated immense interest in exploring their therapeutic potential. Administering probiotics as such not only compromises their viability but also fails to guarantee their successful establishment in gut. In recent times emphasis has been made to take a pharmaceutical approach to probiotics which will not only maintain their viability during storage but will also assist in their successful delivery to and establishment at the site of action in a viable form. Further to above, supplementation of probiotics with prebiotics is also gaining predominance in the recent past. Numerous reports indicate that co-encapsulating prebiotics with probiotics, improves viability of the latter, apart from the independent growth promoting effect of the former on the inherent healthy gut microbiota of the host. The current chapter aims to analyze probiotics as pharmaceuticals, their encapsulation techniques, existing pharmaceutical preparations, their regulatory status in some countries, and future research needs. The current status of prebiotics in health care is also highlighted read more ...