Caister Academic Press

Chronic Wasting Disease and Other Animal Prion Diseases

Akikazu Sakudo
from: Prions: Current Progress in Advanced Research (Edited by: Akikazu Sakudo and Takashi Onodera). Caister Academic Press, U.K. (2013)


Chronic wasting disease (CWD) is one of the prion diseases showing clinical symptoms such as progressive weight loss, abnormal behaviour and excessive salivation. Incidents have been reported in North America and Korea. Efficient transmission by horizontal infection possibly occurs via saliva or faeces. Infectivity in the skeletal muscle of infected deer has been observed, suggesting meat could be a potential source of infection. However, at the moment, CWD transmission to humans is thought to be very unlikely. In this chapter, we also introduce representatives of other animal prion diseases, such as transmissible mink encephalopathy (TME) and feline spongiform encephalopathy (FSE). Recently, possible transmission of CWD to fishes has also been reported read more ...
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