The Genomics of Agrobacterium: Insights into its Pathogenicity, Biocontrol, and Evolution
Joao C. Setubal, Derek Wood, Thomas Burr, Stephen K. Farrand, Barry S. Goldman, Brad Goodner, Leon Otten, and Steven Slater
from: Plant Pathogenic Bacteria: Genomics and Molecular Biology (Edited by: Robert W. Jackson). Caister Academic Press, U.K. (2009)
The genus Agrobacterium belongs to the Rhizobiaceae family of α-Proteobacteria and includes widely found plant pathogens that cause the crown gall and hairy root diseases. A. tumefaciens is also well-known as a natural biotechnological tool thanks to its ability to transfer part of its DNA into plant cells. In this chapter we review current genomic knowledge about three species in this genus: A. tumefaciens C58, A. vitis S4, and A. radiobacter K84, focusing on the genomic basis for virulence determinants, and symbiotic interactions. These organisms have a relatively complex genome architecture, with each genome containing several replicons, and this provides an interesting view into bacterial evolution. In the second half of the chapter we describe this architecture as well as the syntenic relationships between these three species and closely related Rhizobium genomes. An analysis of the secondary large replicons and the smaller plasmids concludes the chapter read more ...