Porcine Reproductive and Respiratory Syndrome Virus
Alexander N. Zakhartchouk, S. K. Pujhari and J.C.S. Harding
from: Porcine Viruses: From Pathogenesis to Strategies for Control (Edited by: Hovakim Zakaryan). Caister Academic Press, U.K. (2019) Pages: 149-180.
Porcine reproductive and respiratory syndrome virus (PRRSV) is a swine arterivirus responsible for reproductive failure and respiratory problems in sows and piglets, respectively. It is one of the most economically devastating diseases of pigs and continues to result in major health challenges in the swine industry worldwide. The virus is continuously evolving and emerges episodically in different regions of the world with increased virulence. In this chapter, we briefly summarize the current understanding of PRRSV from the perspectives of the virus molecular biology, virus-host cell interactions, pathogenesis, diagnostic procedures and epidemiology. We also provide an overview of currently available vaccines and a novel vaccine development read more ...