Caister Academic Press

Porcine Epidemic Diarrhea Virus

Changhee Lee
from: Porcine Viruses: From Pathogenesis to Strategies for Control (Edited by: Hovakim Zakaryan). Caister Academic Press, U.K. (2019) Pages: 107-134.


A novel enteric disease of swine recognized in Europe in the early 1970s was initially named "epidemic diarrhea", and is now called "porcine epidemic diarrhea (PED)". A new coronavirus referred to as PED virus (PEDV) was determined as the etiologic agent of this disease in the late 1970s. PEDV has since plagued Europe and Asia; however, the most severe outbreaks with the greatest economic impact have occurred in Asian swine-producing countries. PED first emerged in the United States in early 2013, caused unprecedented devastating to the pork production industry, and further spread to Canada and Mexico, as well as to South American countries. Promptly thereafter, massive PED epidemics recurred in South Korea, Japan, and Taiwan. Thus, these recent global emergences and re-emergences of PED requires urgent attention, and a deeper and concrete understanding of the molecular biology and pathogenic mechanisms underlying PEDV is required to develop effective vaccines and control strategies. This chapter will emphasize the importance of basic, applied, and translational studies and encourage collaboration among swine producers, researchers, and veterinarians to provide answers that improve our knowledge of PEDV in efforts to prevent and eliminate this economically significant viral disease, as well as to prepare for future epizootics or panzootics of PED read more ...
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