RNA Silencing and the Interplay Between Plants and Viruses
Lourdes Fernández-Calvino, Livia Donaire and César Llave
from: Recent Advances in Plant Virology (Edited by: Carole Caranta, Miguel A. Aranda, Mark Tepfer and J.J. Lopez-Moya). Caister Academic Press, U.K. (2011)
In eukaryotes, RNA silencing controls gene expression to regulate development, genome stability and stress-induced responses. In plants, this process is also recognized as a major immune system targeted against plant viruses. Plant viruses stimulate RNA silencing responses though formation of viral RNA with double-stranded features that are subsequently processed into functional small RNAs (sRNAs). Recent studies highlight the complexity of the viral sRNA populations and their potential to associate with multiple silencing effector complexes. This fact has profound implications in the cross-talk interactions between plants and viruses since both virus genomes and host genes are putative targets of viral sRNAs. In this chapter, the concept of RNA silencing is discussed as an elegant natural antiviral mechanism in plants, assessing the contribution of viral sRNA-mediated regulation of gene expression in the frame of compatible interactions between plants and viruses read more ...