Caister Academic Press

Comparative Genomics of Pasteurellaceae

Jean F. Challacombe and Thomas J. Inzana
from: Pasteurellaceae: Biology, Genomics and Molecular Aspects (Edited by: Peter Kuhnert and Henrik Christensen). Caister Academic Press, U.K. (2008)


The family Pasteurellaceae contains diverse members, including opportunistic pathogens, human and animal pathogens as well as avirulent commensal strains. Although they are related, the diversity of the bacteria comprising this family makes them ideal candidates for comparative genome analysis. In this chapter we review and compare the available genomic information on the sequenced Pasteurellaceae members: Aggregatibacter actinomycetemcomitans strain HK1651, Actinobacillus pleuropneumoniae strains L20 and sv1 4074, [ Haemophilus ] ducreyi strain 35000HP, Haemophilus influenzae strains 86-028NP, R2846, R2866, and Rd, Histophilus somni strains 129Pt and 2336, Mannheimia haemolytica A1 strain ATCC BAA-410, ' Mannheimia succiniciproducens ' strain MBEL55E, and Pasteurella multocida strain Pm70. We also present some example comparisons to demonstrate the utility of the comparative genomics approach for studying this family of bacteria read more ...
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