Broad Spectrum Viral and Bacterial Pathogen Detection by Microarrays
Kevin McLoughlin, Crystal Jaing, Shea Gardner, Nicholas A. Be, James B. Thissen and Tom Slezak
from: Microarrays: Current Technology, Innovations and Applications (Edited by: Zhili He). Caister Academic Press, U.K. (2014)
Broad spectrum viral and bacterial pathogen detection microarrays have proven useful to analyze pathogenic organisms in clinical and environmental samples. The microbial detection arrays are less costly and faster than next generation sequencing, and more comprehensive than single-plex and multiplex PCR assays. Pathogen detection arrays have been used for detection and genotyping of viral and bacterial pathogens for biodefense, public health, and food and drug safety. These arrays have also contributed to the discovery of novel viruses. Pathogen microarrays are cost-effective, rapid genomic assays that are expected to gain a wider use both in research settings and in the regulatory and diagnostic environment read more ...