Optical Sectioning for Microfluidics
Yeh-Chan Ahn and Zhongping Chen
from: Lab-on-a-Chip Technology (Vol. 2): Biomolecular Separation and Analysis (Edited by: Keith E. Herold and Avraham Rasooly). Caister Academic Press, U.K. (2009)
This chapter describes Doppler optical coherence tomography (OCT), a new optical tomographic technique that can image and quantify microstructure and flow simultaneously in microfluidic channel. Doppler OCT is a three-dimensional, non-contact, high-resolution, real-time imaging technique that provides information of wall location and shape in microchannel, three-dimensional velocity profile, and mixing performance. It is a versatile and essential tool for engineers and scientists who want to study transport phenomena in microchannel, to design and test microfluidic components, and to monitor a flaw or malfunction in lab-on-a-chip in situ. System configuration and principle of Doppler OCT are described and several applications are demonstrated read more ...