Nudiviruses: Their Biology and Genetics
Johannes A. Jehle
from: Insect Virology (Edited by: Sassan Asgari and Karyn N. Johnson). Caister Academic Press, U.K. (2010)
Nudiviruses are a diverse group of rod-shaped viruses with large circular closed dsDNA genomes, which have previously been considered as non-occluded baculoviruses, because of the lack of an occlusion body. In this chapter, the biology as well as recent advances in genome sequencing, analysis of gene function and phylogenetic analyses will be reviewed. These studies revealed that nudiviruses are indeed related to baculoviruses and share a set of 20 core genes involved in virus structural components, virus-host interaction, DNA replication, nucleotide metabolism and RNA replication. As shown in this chapter, the lack of an occlusion body is not a suitable demarcation between nudiviruses and baculoviruses, as some nudiviruses produce an occlusion body read more ...