What Does A Vaccine Need to Do to Elicit Protective Immunity Against HIV Infection?
Paul Thottingal and Sarah L. Rowland-Jones
from: AIDS Vaccine Development: Challenges and Opportunities (Edited by: Wayne Koff, Patricia Kahn and Ian D. Gust). Caister Academic Press, U.K. (2007)
Abstract
The unique challenges of generating an effective vaccine to prevent HIV-1 infection have led immunologists to consider in detail the mechanisms of protective immunity that a successful candidate must elicit. This article reviews our current understanding of protective immunity to HIV-1 infection, based on studies of animal models and of exposed but apparently uninfected people read more ...
