Carla Kuiken and Richard Scheuermann
from: Hepatitis C: Antiviral Drug Discovery and Development (Edited by: Seng-Lai Tan and Yupeng He). Caister Academic Press, U.K. (2011)
Sequence databases provide a resource for scientific researchers worldwide that is especially important for highly variably pathogens such as HCV. There are currently a number of HCV sequence databases, two of which will be discussed in detail in this review. The Los Alamos HCV sequence database has been widely used since 2004, and still is a commonly used resource. A new addition is the Virus Pathogen Resource, which contains sequences from viral pathogens from many different families, and does not focus on HCV. We compare mission, features, and future plans of both databases and attempt to provide some guidance to help users decide which resource is more useful for specific data analysis problems read more ...