Applying Proteomics to Investigate the Interactions Between Pathogenic Fusarium Species and Their Hosts
Linda J. Harris, Thérèse Ouellet and Rajagopal Subramaniam
from: Fusarium: Genomics, Molecular and Cellular Biology (Edited by: Daren W. Brown and Robert H. Proctor). Caister Academic Press, U.K. (2013)
The recent technical advances in mass spectrometry (MS) such as tandem MS (MS/MS) and gel and non-gel-based methods of protein separation and quantification have galvanized research efforts to study the proteomes of pathogenic fungi. The acquisition of high quality genomic sequences has provided the species-specific protein databases essential for successful assignment of sequenced peptides to fungal proteins. Proteomics can be defined as defining the complete set of protein species present in a living organism. While transcriptomics describes the transcripts available for translation, proteomics tells us which proteins have actually been translated, modified, and are available for facilitating cellular processes. This review touches on how proteomics has been exploited to further explore biological questions involving Fusarium species read more ...