Epidemiology, Pathogenesis, Ecology and Genetics of Listeria monocytogenes
Sangmi Lee, Robin M. Siletzky and Sophia Kathariou
from: Foodborne and Waterborne Bacterial Pathogens: Epidemiology, Evolution and Molecular Biology (Edited by: Shah M. Faruque). Caister Academic Press, U.K. (2012)
Listeria monocytogenes is a Gram-positive foodborne pathogen that causes a severe, potentially fatal illness (listeriosis) in animals and humans. The only human pathogen within the genus Listeria, this bacterium is equipped with sophisticated mechanisms to invade mammalian cells and proliferate inracellularly. Population genetics data indicate that some groups of L. monocytogenes are more frequently associated with human listeriosis. However, the ecology and potentially unique characteristics of such groups remain to be elucidated. This chapter discusses recent advances in the epidemiology of listeriosis and epidemic-associated clonal groups; the characterization of pathogenicity of L. monocytogenes; the evolution of Listeria species and L. monocytogenes; and the increasingly recognized importance of Listeria phages in the ecology of L. monocytogenes in food processing facilities read more ...