Avian Influenza H7N9 Virus
Ying Wu, Yi Shi, Jun Liu, Yan Wu and George F. Gao
from: Influenza: Current Research (Edited by: Qinghua Wang and Yizhi Jane Tao). Caister Academic Press, U.K. (2016) Pages: 139-160.
In March 2013, the first cases of human infection with a novel reassortant of avian influenza A virus (H7N9) were reported in China. The rapid increase in cases with considerable morbidity and mortality over a subsequent brief time period has posed a great threat to public health globally. In this chapter we present an overview of the current understanding of H7N9 virus from the perspectives of the virus origin, clinical features and treatments of virus infection, host immune responses, virus receptor-binding properties as well as drug resistance. We also provide a snapshot of vaccine development and monoclonal antibody application against H7N9 virus infection and call for precautionary measurements for unpredictable emergence of novel reassortants of influenza viruses, HxNy read more ...