Vaccines Against Enteric E. coli Infections in Animals
Eric Cox, Vesna Melkebeek, Bert Devriendt, Bruno M. Goddeeris and Daisy Vanrompay
from: Pathogenic Escherichia coli: Molecular and Cellular Microbiology (Edited by: Stefano Morabito). Caister Academic Press, U.K. (2014)
Several E. coli animal pathogens exist, which have an important economical impact, such as enterotoxigenic E. coli, avian pathogenic E. coli and mammary pathogenic E. coli. Furthermore, ruminants are carrier of enterohemorrhagic E. coli, which are not pathogenic for them, but can be transmitted to humans via direct contact and contamination of food or drinks, resulting in severe disease. Nevertheless, only few E. coli vaccines are available. This chapter summarizes the current status of vaccines for preventing intestinal E. coli infections in animals and will deal with vaccines against ETEC infections in pigs and ruminants and vaccines, which prevent EHEC colonization in cattle read more ...