Proteomic Analysis of Post Translational Modifications in Cyanobacteria
Qian Xiong, Zhuo Chen and Feng Ge
from: Cyanobacteria: Omics and Manipulation (Edited by: Dmitry A. Los). Caister Academic Press, U.K. (2017) Pages: 145-160.
Cyanobacteria are a diverse group of Gram-negative bacteria and the only prokaryotes capable of oxygenic photosynthesis. Recently, cyanobacteria have attracted great interest due to their crucial roles in global carbon and nitrogen cycles and their ability to produce clean and renewable biofuels. To survive at various environmental conditions, cyanobacteria have developed a complex signal transduction network to sense environmental signals and implement adaptive changes. The post-translational modifications (PTMs) systems play important regulatory roles in the signaling networks of cyanobacteria. Mass spectrometry (MS)-based proteomic technologies have been applied to identify PTMs in a systematic manner. Although the proteomic studies of PTMs carried out in cyanobacteria were limited, these data have provided clues to elucidate their sophisticated sensing mechanisms that contribute to their evolutionary and ecological success. This chapter aims to summarize the current status of PTM studies and recent publications regarding PTM proteomics in cyanobacteria, and discuss the novel developments and applications for the analysis of PTMs in cyanobacteria. Challenges, opportunities, and future perspectives in the proteomics studies of PTMs in cyanobacteria are also discussed read more ...