Transcriptomics of Cyanobacterial Stress Responses: Genes, Sensors, and Molecular Triggers
Maria A. Sinetova, Anna A. Zorina, Kirill S. Mironov and Dmitry A. Los
from: Cyanobacteria: Omics and Manipulation (Edited by: Dmitry A. Los). Caister Academic Press, U.K. (2017) Pages: 93-116.
Systemic analysis of transcriptomes of the cyanobacterium Synechocystis sp. PCC 6803 revealed that all stress-induced genes can be separated into two groups: one is clustered around heat-shock- and another around cold-shock-inducible genes. At the initial stages of stress (in a range of 15-20 min) genes induced by heat and cold stress never overlap. Genes for so-called heat shock proteins (HSPs) are induced by various stressors, e.g. heat, salt, hyperosmotic environment, reactive oxygen species (ROS), changes in light intensity and quality, or in the redox potential of the photosynthetic electron transport chain components. The number of specifically heat-induced genes is rather limited and their functions are mostly unknown. Cold-stress-induced genes also overlap, but with different sets of genes induced by all above mentioned stressors with the exception of heat stress. The analysis suggests that ROS (in particular, H2O2) and redox changes of the components of the photosynthetic electron chain may function as universal triggers for stress responses in cyanobacteria read more ...