Biotechnological Application of Corynebacterium glutamicum Under Oxygen Deprivation
Toru Jojima, Masayuki Inui and Hideaki Yukawa
from: Corynebacterium glutamicum: From Systems Biology to Biotechnological Applications (Edited by: Andreas Burkovski). Caister Academic Press, U.K. (2015) Pages: 151-160.
Traditional bioprocesses using Corynebacterium glutamicum as biocatalysts, including amino acid fermentation process, are operated under aerobic conditions. An emerging bioprocess in which the microorganism is utilized under oxygen deprivation, so-called growth-arrested bioprocess, is from these traditional fermentation processes. This novel bioprocess is expected to play a major role in the production of biofuels, commodity and fine chemicals, besides the aforementioned amino acids. In this chapter, we describe the physiology of C. glutamicum under oxygen deprived conditions with respect to recent advances in development of the microorganism as a mainstay biocatalysts used in growth-arrested bioprocess, with special emphasis on potential applications relevant to future lignocellulosic biorefineries read more ...