Caister Academic Press

Phosphorus Metabolism and its Regulation

Volker F. Wendisch and Michael Bott
from: Corynebacteria: Genomics and Molecular Biology (Edited by: Andreas Burkovski). Caister Academic Press, U.K. (2008)


The phosphorus metabolism of Corynebacterium glutamicum and its regulation have been studied to some detail using a combination of genetic, biochemical and transcriptome analyses. C. glutamicum utilizes a number of inorganic and organic phosphates as sources of phosphorus. When orthophosphate (Pi), its preferred phosphorus source, is abundant, C. glutamicum accumulates polyphosphate. When Pi becomes scarce, a complex genetic response is elicited enabling C. glutamicum to scavenge low Pi concentrations, to take up transportable organophosphates and to access Pi from nontransportable Pi esters. The two-component signal transduction system PhoS-PhoR serves a role in the transcriptional regulation of the Pi starvation-inducible genes read more ...
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