DNA Microarray-based Transcriptome Analysis in C. glutamicum
Volker F. Wendisch
from: Corynebacteria: Genomics and Molecular Biology (Edited by: Andreas Burkovski). Caister Academic Press, U.K. (2008)
Since the availability of DNA microarray technology for Corynebacterium glutamicum and completion of the genome sequence, transcriptome analyses have immensely contributed to further our understanding of this bacterium, a non-pathogenic actinomycete of biotechnological importance. This chapter describes the use of DNA microarray-based transcriptome analyses to elucidate global gene expression changes in response to environmental changes (stimulons), to determine targets of transcriptional regulators (regulons), to map undirected mutations and to improve amino acid production by C. glutamicum read more ...