The Intricate Relationship Between Campylobacter and Mucus
Claire Shortt, Gina Duggan and Billy Bourke
from: Campylobacter Ecology and Evolution (Edited by: Samuel K. Sheppard). Caister Academic Press, U.K. (2014)
Abstract
For any successful mucosal pathogen a key early step in the infection sequence is to establish effective colonisation of the mucus layer. Campylobacters have evolved to live as commensals in the mucus of avian species. In disease in humans these organisms can breach the mucus defence systems and interact directly with intestinal epithelial cells. Recent insights into the role of mucus in protecting the intestine and the influence of mucus on the behaviour and adaptaion of C. jejuni, has led to a much better understanding of the ecology of C. jejuni in the supra mucosal niche read more ...
