Concerted Evolution in Campylobacter jejuni and Campylobacter coli
Richard J. Meinersmann
from: Campylobacter Ecology and Evolution (Edited by: Samuel K. Sheppard). Caister Academic Press, U.K. (2014)
Abstract
Concerted evolution is the phenomenon in which multiple copies of genes maintain sequence similarity in a single individual while the genes continue to diverge between individuals. Concerted evolution has been described in Campylobacter jejuni and C. coli for the pair of flagellin genes, which are notable for their diversity, the 23S ribosomal RNA genes, which are notable for the degree that they are conserved, and for the portion of the ribosomal operon between the 16S and 23S genes. The evidence for concerted evolution is presented and the biological implications are discussed in this review. An interesting case is the concerted evolution of the 23S rRNA genes that is needed to rapidly become resistant to macrolides. Understanding which genes are affected by concerted evolution will allow proper assessment of probable phylogenetic distortions that will be seen with such genes read more ...
