Caister Academic Press

Comparative Transcriptomics in Burkholderia

Andrea Sass, Pavel Drevinek and Pam A Sokol
from: Burkholderia: From Genomes to Function (Edited by: Tom Coenye and Eshwar Mahenthiralingam). Caister Academic Press, U.K. (2014)


The advance in sequencing technologies and the availablility of whole genome sequences enabled studying the entire transcriptome of organisms, either by microarray analysis or RNA sequencing. Burkholderia species for which such gene expression studies have been performed include B. cenocepacia, B. pseudomallei, B. mallei, B. xenovorans, B. ambifaria, and B. multivorans. This review focusses on findings in the areas of resistance to antibiotics, to biocides and to oxidative stress, iron transport, quorum sensing, mucoidy and host adaptation in these Burkholderia sp., obtained by means of global differential transcriptome analysis read more ...
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