Caister Academic Press

Biosynthesis and Application of Poly(gamma-glutamic acid)

Ing-Lung Shih and Jane-Yil Wu
from: Microbial Production of Biopolymers and Polymer Precursors: Applications and Perspectives (Edited by: Bernd H. A. Rehm). Caister Academic Press, U.K. (2009)


This review chapter deals with chemistry and biosynthesis of poly-γ-glutamic acid (γ-PGA) produced by various strains of Bacillus. In addition to the production, purification and characterization of γ-PGA, an updated critical literature review on the physiological function, biochemical and chemical properties, genetic aspects and enzymology of γ-PGA metabolism (racemization, polymerization and degradation), the molecular mechanism of glutamic acid polymerization were provided. Potential applications of γ-PGA as thickener, cryoprotectant, humectant, drug carrier, biological adhesive, flocculant, or heavy metal absorbent with biodegradability in the fields of food, cosmetics, medicine, water treatments and environment were also reviewed read more ...
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