Visual Restoration using Microbial Rhodopsins
Nicole L. Wagner, Jordan A. Greco and Robert R. Birge
from: Bionanotechnology: Biological Self-assembly and its Applications (Edited by: Bernd H. A. Rehm). Caister Academic Press, U.K. (2013)
Biological systems are governed by nano- and micro- scale processes that can be efficiently exploited by various technological tools and research approaches. Harnessing the power of nanobiotechnology has modified the way scientists approach and treat diseases. Through manipulation of matter at the nanoscale regime, engineers now have the ability to attack many of the challenges of modern science and medicine. As the field of nanotechnology and nanobiotechnology grows, new paradigms are being developed to accentuate the development of nanometric and micrometric materials and devices. This review will focus on the use of retinylidene proteins, particularly microbial rhodopsins, in gene therapy, optogenetics, and visual prosthetics for the treatment of opthalmic degenerative diseases read more ...