Mechanism of Biofilm Formation in Gram-Negative Bacteria
Ulrich Vasconcelos, Palashpriya Das, Diogo Simas Bernardes Dias, Tarcísio Tárcio Correa Bonifácio, Ray Ravilly Alves Arruda, Bianca Teixeira Morais de Oliveira and Thiago Gonçalves Cavalcanti
from: Microbial Biofilms: Current Research and Practical Implications (Edited by: Arindam Mitra). Caister Academic Press, U.K. (2020) Pages: 75-98.
Abstract
Biofilms consist of one or more microbial species of microbes living in close association. Mixed species biofilms are more predominant in the environment. Though biofilm imparts various advantages to its producer, huge economic losses are encountered because of biofilm formation and has been described with special emphasis on Pseudomonas aeruginosa. However, recent studies on human microbiota imply that biofilm formation helps in maintenance of human health as well so it is wholly not harmful only. While physicochemical factors like temperature, oxygen, light, compounds like antibiotics etc. can affect the process of biofilm formation, this process also involves various genes. The interplay of the genes and the resultant products in various conditions together result in biofilm formation in different microorganisms. Since the first models on understandings of biofilms were evaluated in Gram-negative bacteria, the present review summarizes all parameters that might be affecting this preferred form of microbial sustenance in different Gram-negative bacteria read more ...
