Microbial Elimination of Endocrine Disrupting Compounds
Jerzy Długoński
from: Microbial Biodegradation: From Omics to Function and Application (Edited by: Jerzy Długoński). Caister Academic Press, U.K. (2016) Pages: 99-118.
Abstract
Endocrine disrupting compounds (EDCs) are chemicals that interfere with the proper functioning of the endocrine system in humans and animals, modulating it in a way that favors the activity of female sex hormones (estrogens). As well as being slowly degraded by microorganisms, EDCs are insufficiently eliminated in waste water treatment plants. Some of the compounds are discharged into aquatic environments in quantities of a few to tens of ngl-1 where they can accumulate in the bodies of different organisms (including humans) and subsequently stimulate numerous deleterious changes including fertility disorders and cancer processes.
In this chapter special attention is focused on the mechanisms of microbial detoxification and elimination of EDCs and the accomplishments of recent lipidomic, proteomic and metabolomic studies in these topics . This review also provides the results of the latest research on the parallel elimination of EDCs and heavy metals in saline environments, which has practical significance for the development of effective strategies for the removal of complex pollutants from contaminated areas read more ...
