Bats and Flaviviruses
Andres Moreira-Soto and Eugenia Corrales-Aguilar
from: Bats and Viruses: Current Research and Future Trends (Edited by: Eugenia Corrales-Aguilar and Martin Schwemmle). Caister Academic Press, U.K. (2020) Pages: 7-26.
Bats have been associated as reservoir hosts of viruses of public health importance, such as SARS or henipaviruses. However, for flaviviruses, viruses that are mainly transmitted by arthropod vectors, the link has been difficult to prove. This comprehensive review of the literature analyses in vitro and in vivo experiments, as well as viral isolation and molecular and serological detection of flaviviruses in bats. Later, findings involving and/or excluding bats as hosts, reservoirs or even their putative involvement in the flaviviral transmission cycles are discussed. These confounding discoveries prime to a much needed multidisciplinary approach to prove or disprove the role of bats as hosts for these viruses and to finally clarify if they do play an important role in their transmission cycles read more ...