Functional Genomics of Stress Response in Extremophilic Archaea
Sabrina Tachdjian, Keith R. Shockley, Shannon B. Conners and Robert M. Kelly
from: Archaea: New Models for Prokaryotic Biology (Edited by: Paul Blum). Caister Academic Press, U.K. (2008)
Given that some members of the Archaea inhabit extreme environments while others occupy more hospitable biological niches, the mechanisms by which this group of microorganisms handles stress are well worth examining for clues to prokaryotic "disaster" management. The availability of genome sequence information for a number of archaea has provided a glimpse into the genetic basis for thriving at extremes of temperature, salinity, pH and metal concentrations. Such information has furthermore enabled the application of "omics" tools to examine the phenotype that results from perturbations that trigger both global and focused survival strategies read more ...