Caister Academic Press

Microorganisms Producing Antibiotics

János Bérdy
from: Antibiotics: Current Innovations and Future Trends (Edited by: Sergio Sánchez and Arnold L. Demain). Caister Academic Press, U.K. (2015) Pages: 49-64.


The meaning of the definition of antibiotics, that is the bioactive secondary microbial metabolites, and specific features of the history of antibiotic research in the last eighty years shows continuous changing. The real role of the microbial metabolites in the various life processes in the Earth is far to be totally explored. Their importance, over the antibiotic effect, seems to be more significant than in was believed. They may be general regulatory and signally compounds in the most life processes and in the environment.

The main producers of the microbial metabolites, the actinobacteria, fungi and other filamentous bacteria, represent inexhaustible sources for the future. The connecting and increasing taxonomic, chemical and biodiversities of microbial metabolites certainly will give numerous new leads and drugs and other products not only for the chemotherapy but in other fields of human therapy and also for the agriculture to cure and feed the increasing population.

The numbers of known and possible secondary metabolite producing microorganisms, the produced new chemical compounds and their extremely wide range of bioactivities are discussed in details. Several new trends of the research, the full exploration of the living world of oceans and the discovery of endophytic microbes are also presented read more ...

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