JMMB Volume 3 Number 2

JMMB Volume 3 Number 2. April 2001

Microbial Multidrug Efflux: Introduction
Ian T. Paulsen and Kim Lewis [access full article]

Comparative Genomics of Microbial Drug Efflux Systems
Ian T. Paulsen, Joan Chen, Karen E. Nelson, and Milton H. Saier, Jr [access full article]

The Ostensible Paradox of Multidrug Recognition
Alex A. Neyfakh [access full article]

Precious Things Come in Little Packages
Shimon Schuldiner, Dorit Granot, Sonia Steiner Mordoch, Shira Ninio, Dvir Rotem, Michael Soskin, and Hagit Yerushalmi [access full article]

Staphylococcal Multidrug Efflux Protein QacA
Melissa H. Brown and Ronald A. Skurray [access full article]

MdfA, an Interesting Model Protein for Studying Multidrug Transport
Eitan Bibi, Julia Adler, Oded Lewinson, and Rotem Edgar [access full article]

Enterococcus faecalis Multi-Drug Resistance Transporters: Application for Antibiotic Discovery
Deborah vR. Davis, James B. McAlpine, Christopher J. Pazoles, M. Kelly Talbot, Elisabeth A. Alder, Abbie C. White, Brandie M. Jonas, Barbara E. Murray, George M. Weinstock, and Bruce L. Rogers [access full article]

Molecular Basis of Multidrug Transport by ATP-Binding Cassette Transporters: A Proposed Two-Cylinder Engine Model
Hendrik W. van Veen, Christopher F. Higgins, and Wil N. Konings [access full article]

Prokaryote Multidrug Efflux Proteins of the Major Facilitator Superfamily: Amplified Expression, Purification and Characterisation
Alison Ward, Chris Hoyle, Sarah Palmer, John O'Reilly, Jeff Griffith, Martin Pos, Scott Morrison, Bert Poolman, Mick Gwynne, and Peter Henderson [access full article]

Multidrug Resistance and ABC Transporters in Parasitic Protozoa
Marc Ouellette, Danielle Légaré, and Barbara Papadopoulou [access full article]

The Pleitropic Drug ABC Transporters from Saccharomyces cerevisiae
Bruce Rogers, Anabelle Decottignies, Marcin Kolaczkowski, Elvira Carvajal, Elisabetta Balzi, and André Goffeau [access full article]

AcrAB and Related Multidrug Efflux Pumps of Escherichia coli
Hiroshi Nikaido and Helen I. Zgurskaya [access full article]

Genetic Organization and Regulation of Antimicrobial Efflux Systems Possessed by Neisseria gonorrhoeae and Neisseria meningitidis
William M. Shafer, Wendy L. Veal, Eun-Hee Lee, Leticia Zarantonelli, Jacqueline T. Balthazar, and Corinne Rouquette [access full article]

Inhibition of Efflux Pumps as a Novel Approach to Combat Drug Resistance in Bacteria
Olga Lomovskaya and Will Watkins [access full article]

Functions of Tetracycline Efflux Proteins that Do Not Involve Tetracycline
Terry A. Krulwich, Jie Jin, Arthur A. Guffanti, and David H. Bechhofer [access full article]

In Search of Natural Substrates and Inhibitors of MDR Pumps
Kim Lewis [access full article]

Multidrug Efflux Pumps and Antimicrobial Resistance in Pseudomonas aeruginosa and Related Organisms
Keith Poole [access full article]

JMMB Reviews

Practical Mechanisms for Interrupting the Oral-fecal Lifecycle of Escherichia coli
James B. Russell and Graeme N. Jarvis [access full article]

The Diheme Cytochrome b Subunit (NarI) of Escherichia coli Nitrate Reductase A (NarGHI): Structure, Function, and Interaction with Quinols
Richard A. Rothery, Francis Blasco, Axel Magalon, and Joel H. Weiner [access full article]

JMMB Bioinformatics Corner

A Web-Based Program for the Prediction of Average Hydropathy, Average Amphipathicity and Average Similarity of Multiply Aligned Homologous Proteins
Yufeng Zhai and Milton H. Saier, Jr [access full article]

JMMB Research Articles

SigB, SigC, and SigE from Myxococcus xanthus Homologous to s³² are Not Required for Heat Shock Response but for Multicellular Differentiation
Toshiyuki Ueki and Sumiko Inouye [access full article]

Pyruvate Carboxylase is a Major Bottleneck for Glutamate and Lysine Production by Corynebacterium glutamicum
Petra G. Peters-Wendisch, Bettina Schiel, Volker F. Wendisch, Efstratios Katsoulidis, Bettina Möckel, Hermann Sahm, and Bernhard J. Eikmanns [access full article]

Expression and Isolation of Antimicrobial Small Molecules from Soil DNA Libraries
I.A. MacNeil, C. L. Tiong, C. Minor, P.R. August, T.H. Grossman, K.A. Loiacono, B.A. Lynch, T. Phillips, S. Narula, R. Sundaramoorthi, A. Tyler, T. Aldredge, H. Long, M. Gilman, D. Holt, and M.S. Osburne [access full article]

The PecM Protein of the Phytopathogenic Bacterium Erwinia chrysanthemi, Membrane Topology and Possible Involvement in the Efflux of the Blue Pigment Indigoidine
Carine Rouanet and William Nasser [access full article]

Comparative Approach to Analysis of Regulation in Complete Genomes: Multidrug Resistance Systems in Gamma-Proteobacteria
Dmitry A. Rodionov, Mikhail S. Gelfand, Andrey A. Mironov, and Alexandra B. Rakhmaninova [access full article]