Caister Academic Press

Nanotechnology in Therapeutics: Current Technology and Applications

Publisher: Horizon Bioscience
Editors: Nicholas A. Peppas1, J. Zach Hilt2 and J. Brock Thomas1
1The University of Texas, Austin, USA
2University of Kentucky, Lexington, USA

Publication date: March 2007
ISBN: 978-1-904933-29-8 (hardback)
ISBN: 978-1-904933-40-3 (ebook)
Pages: x + 440

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Nanotechnology is a multidisciplinary field covering a large and diverse array of devices and materials in nanometre scale, derived from engineering, physics, chemistry and biology. The field of applied nanotechnology in medicine is growing fast and the application of nanotechnology to therapeutics has led to advances in drug delivery, biomaterials, biomedical devices, intelligent processes and in many other areas of medicine and applied biomedical sciences.

The authors of this volume describe and discuss current technology and the applications of nanoparticles and nanostructures in various aspects of therapeutics and drug delivery. The chapters are completely up-to-date and are written by some of the leading scientists in the field. Topics covered include chronobiology, chronopharmacology and chronotherapeutics, polymeric gene delivery vectors, biohybrid materials, biomimetic systems, hydrogel nanocomposites, star polymers and dendrimers, ionic nanoparticulate systems, nanospheres and nanoparticles. Entire chapters are devoted to specific applications of nanotechnology such as cancer therapy, bone disorders, and diabetes.

An essential book for anyone interested in the application of nanotechnology in medicine.

Chapter List:

Section A. Intelligent Therapeutics and Responsive Delivery Systems for Improved Absorption and Delivery

Chapter 1
Concepts of Medical Chronobiology, Chronopharmacology and Chronotherapeutics as the Basis for Applications of Drug Delivery Technology
Nicholas A. Peppas

Chapter 2
Feedback Control in Drug Delivery
Jeffry A. Florian, Jr. and Robert S. Parker

Chapter 3
Advances in Drug Delivery Technologies for Nanoparticulates
Robert O. Williams III and Kirk A. Overhoff

Chapter 4
Synthetic Ligand-Receptor Interactions In Delivery Systems
David B. Henthorn, Youyou Zheng and Nicholas A. Peppas

Chapter 5
Nanoscale Analysis of Mucus-Carrier Interactions for Improved Drug Absorption
Yanbin Huang and Nicholas A. Peppas

Chapter 6
Polymeric Gene Delivery Vectors
Han Chang Kang, Minhyung Lee and You Han Bae

Section B. Therapeutic Micro- and Nanodevices

Chapter 7
Biohybrid Materials for Therapeutic Devices
Elizabeth A. Moschou, Leonidas G. Bachas and Sylvia Daunert

Chapter 8
Biomimetic Systems: A Synergy of Scientific and Engineering Approaches
Mark E. Byrne and Siddarth Venkatesh

Chapter 9     (Addendum - Table 9.2)
Nanostructured Scaffolds for Tissue Engineering
Danielle S.W. Benoit and Kristi S. Anseth

Section C. Nanostructured Therapeutic Materials

Chapter 10
Hydrogel Nanocomposites for Intelligent Therapeutics
Reynolds A. Frimpong and J. Zach Hilt

Chapter 11
Nanotechnology for Treating Bone Disorders
Ganesan Balasundaram, Grace Park and Thomas J. Webster

Chapter 12
Nanotechnology and Cancer Therapy
James O. Blanchette and Nicholas A. Peppas

Section D. Nanoparticulate Systems in Intelligent Therapy

Chapter 13
Star Polymers and Dendrimers in Nanotechnology and Drug Delivery
Stephanie Seidlits and Nicholas A. Peppas

Chapter 14
Ionic Nanoparticulate Systems for Drug Delivery
Petr Bures and Nicholas A. Peppas

Chapter 15
Nanospheres of Intelligent Networks for Biomedical and Drug Delivery Applications
Nicholas A. Peppas and Daphne N. Robinson

Chapter 16
Shell Crosslinked Nanoparticles: A Progress Report of their Design for Drug Delivery
Yali Li, Guorong Sun, Jinqi Xu and Karen L. Wooley

Chapter 17
Nanoparticulate Structures in Diabetes Treatment
Nicholas A. Peppas and C. Donini


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