Caister Academic Press

Foot and Mouth Disease: Current Perspectives

Publisher: Horizon Bioscience
Editors: Francisco Sobrino and Esteban Domingo Universidad Autónoma de Madrid and the Centro de Investigación au Sanidad Animal, Madrid, Spain
Publication date: August 2004
ISBN-10: 0-8493-2951-5
ISBN-13: 978-0-8493-2951-7
Pages: xii + 458

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Renewed interest in FMD research worldwide has led to a huge increase in the amount of scientific data generated. This volume will help keep the busy scientist up-to-date with all the latest developments. Interdisciplinary in approach, the book provides for the first time a coherent picture of the emerging strategies for diagnosis and control. With contributions from leading international FMD researchers, the volume provides comprehensive coverage of the entire area. Topics covered include genome organisation, translation and replication of FMD virus RNA, proteinases, virus particles, clinical signs of FMD, viral persistence, host range, immunology, quasispecies dynamics and evolution, vaccines, and much much more.

Essential reading for everyone with an interest in FMD: virologists, molecular biologists, biotechnologists,college lecturers, veterinary practioners, and pharmaceutical and biotechnology companies.

Financial support for the production of part of the color plates at the back of the book was generously provided by Fundación Wellcome España.


"... an authoritative and compelling overview of FMD with a greater breadth and depth than any so far. I would highly recommend it for anybody with a specific interest in the biology and/or control of FMD or as an institute purchase for virology departments." from SGM Microbiol. Today (2005).

Chapter List:

Chapter 1: Stepping Stones in Foot-and-Mouth Research: A Personal View
F. Brown

Chapter 2: Genome Organisation, Translation and Replication of Foot-and-Mouth Disease Virus RNA
Graham J. Belsham and Encarnacion Martinez-Salas

Chapter 3: Foot-and-Mouth Disease Virus Proteinases
Martin D. Ryan, Michelle L.L. Donnelly, Mike Flint, Vanessa M. Cowton, Garry Luke, Lorraine E. Hughes, Caroline Knox and Pablo de Felipe

Chapter 4: Structure of Foot-and-Mouth Disease Virus Particles
Cristina Ferrer-Orta and Ignacio Fita

Chapter 5: Clinical Signs of Foot-and-Mouth Disease
Alex Donaldson

Chapter 6: Persistence of Foot-and-Mouth Disease Virus
J. S. Salt

Chapter 7: Molecular Aspects of Foot-and-Mouth Disease Virus Virulence and Host Range: Role of Host Cell Receptors and Viral Factors
Barry Baxt and Elizabeth Rieder

Chapter 8: Immunology of Foot- and- Mouth Disease
Kenneth C. McCullough and Francisco Sobrino

Chapter 9: Functional and Structural Aspects of the Interaction of Foot-and-Mouth Disease Virus with Antibodies
Mauricio G. Mateu and Nuria Verdaguer

Chapter 10: Quasispecies Dynamics and Evolution of Foot-and-Mouth Disease Virus
Esteban Domingo, Carmen M. Ruiz-Jarabo, Armando Arias, Juan García-Arriaza and Cristina Escarmís

Chapter 11: Modern Inactivated Foot-and-Mouth Disease (FMD) Vaccines: Historical Background and Key Elements in Production and Use
S.J. Barteling

Chapter 12: Foot-and-Mouth Disease Virus Peptide Vaccines
David J. Rowlands

Chapter 13: Mathematical Models of the Epidemiology and Control of Foot-and-Mouth Disease
Mark E.J. Woolhouse

Chapter 14: Natural Habitats in which Foot-and-Mouth Disease Viruses are Maintained
Wilna Vosloo and Gavin R. Thomson

Chapter 15: Diagnosis and Control of Foot-and-Mouth Disease

Chapter 16: Control of Foot-And-Mouth Disease: Role of International Organizations
J. Blancou, Y. Leforban, J. E. Pearson

Chapter 17: Overview of Foot-and-Mouth Disease and its Impactas a Re-Emergent Viral Infection
Brian W.J. Mahy

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(EAN: 9780849329517)