Caister Academic Press

Campylobacter: Molecular and Cellular Biology

Publisher: Horizon Bioscience
Editor: Julian M. Ketley Department of Genetics, University of Leicester, Leicester UK and Michael E. Konkel Washington State University, School of Molecular Biosciences, Pullman, WA 99164-4234, USA
Publication date: 01 Jan 2005
ISBN-10: 1-904933-05-X
ISBN-13: 978-1-904933-05-2
Pages: x + 453

How to Order

The publication of the complete sequence of the C. jejuni genome in 2000 provided new insight into this leading gastrointestinal pathogen and presented scientists with an exciting resource to improve our understanding of the biology of this bacterium. In this book internationally recognised Campylobacter experts critically review the most important aspects of Campylobacter research, providing the first coherent picture of the organism's molecular and cellular biology since the publication of the genome. Most contributions are written from a molecular and genomic perspective and contain speculative models upon which to base future research efforts. Introductory chapters explore the taxonomy, genetic diversity, habitats, and epidemiological analysis of campylobacters. Other chapters review Campylobacter plasmid biology, antimicrobial resistance, stress response, motility, chemotaxis, metabolism and bioenergetics of C. jejuni, and polysaccharide biosynthesis (including lipooligosaccharide, capsule biosynthesis, and protein glycosylation). The final chapters focus more directly on interactions with the host, for example, the mechanisms of host cell invasion, interactions with phagocytes, and the use of microarrays to analyze gene expression in response to infection by C. jejuni. Each chapter is independent and can be read in isolation, but as a whole the book provides an important resource summarising our current knowledge of Campylobacter molecular and cellular biology. Essential reading for all researchers working with Campylobacter and related organisms.

Key Features:

* Every aspect of Campylobacter Research covered
* Expert International Authors
* Fully Up-To-Date
* Broad Coverage
* Comprehensive Reference Section


"This book provides an excellent resource for current reviews on the molecular and cellular biology of Campylobacter. All important aspects of the biology of this organism are reviewed and useful models are presented as the basis for future research ... essential reading for all researchers working with Campylobacter ... a useful institutional resource, particularly for scientists and students interested in infection biology and microbial pathogenesis." from Microbiology Today (2005) August issue.

"a useful update ... " from The Quarterly Review of Biology (2006) 81: 64.

Chapter List:

Chapter 1
Campylobacter Infection - Clinical Context
Vincent B. Young and Linda S. Mansfield

Chapter 2
Taxonomy, Phylogeny, and Methods for the Identification of Campylobacter Species
Stephen L. W. On

Chapter 3
Population Genetics of Campylobacter jejuni
Kate E. Dingle and Martin C.J. Maiden

Chapter 4
Campylobacter jejuni Strain Variation
Collette Fitzgerald, Andrew D. Sails and Patricia I. Fields

Chapter 5
Advances in Campylobacter jejuni Comparative Genomics through Whole Genome DNA Microarrays
Nick Dorrell, Olivia L. Champion and Brendan W. Wren

Chapter 6
Prevalence of Campylobacter in the Food and Water Supply: Incidence, Outbreaks, Isolation and Detection
William G. Miller and Robert E. Mandrell

Chapter 7
Methods for Epidemiological Analysis of Campylobacter jejuni
John D. Klena and Michael E. Konkel

Chapter 8
Plasmids of Campylobacter jejuni 81-176
Joseph C. Larsen and Patricia Guerry

Chapter 9
Mechanisms of Antimicrobial Resistance in Campylobacter
Diane E. Taylor and Dobryan M. Tracz

Chapter 10
Multidrug Efflux Systems in Campylobacter
Jun Lin, Masato Akiba and Qijing Zhang

Chapter 11
Genetic Bases for the Variation in the Lipooligosaccharide Outer Core of Campylobacter jejuni and Possible Association of Glycosyltransferase Genes with Post-infectious Neuropathies
Michel Gilbert, Peggy C.R. Godschalk, Craig T. Parker, Hubert Ph. Endtz and Warren W. Wakarchuk

Chapter 12
The Polysaccharide Capsule of Campylobacter jejuni
A.V. Karlyshev, O.L. Champion, G.W.P. Joshua and B.W. Wren

Chapter 13
Protein Glycosylation in Campylobacter
Christine M. Szymanski, Scarlett Goon, Brenda Allan and Patricia Guerry

Chapter 14
Metabolism, Electron Transport and Bioenergetics of Campylobacter jejuni: Implications for Understanding Life in the Gut and Survival in the Environment
David J. Kelly

Chapter 15
Iron Transport and Regulation
Karl G. Wooldridge and Arnoud H.M. van Vliet

Chapter 16
Campylobacter jejuni Stress Responses During Survival in the Food Chain and Colonization
Simon F. Park

Chapter 17
Aparna Jagannathan and Charles Penn

Chapter 18
Campylobacter Chemotaxis
Victoria Korolik and Julian Ketley

Chapter 19
Lan Hu and Dennis J. Kopecko

Chapter 20
Cytolethal Distending Toxin
Carol L. Pickett and Robert B. Lee

Chapter 21
Interactions of Campylobacter jejuni with Non-professional Phagocytic Cells
Brian H. Raphael, Marshall R. Monteville, John D. Klena, Lynn A. Joens and Michael E. Konkel

Chapter 22
Campylobacter jejuni Interactions with Professional Phagocytes
Lynn Joens

Chapter 23
Campylobacter spp. and the Ability to Elicit Intestinal Inflammatory Responses
Paul Everest

Chapter 24
Campylobacter jejuni Interaction with Enterocytes - Using Host Gene Expression Analysis to Unravel Potential Disease Mechanisms
Amanda MacCallum, Pawel Herzyk, Catriona Young, Julian Ketley and Paul Everest

How to buy this book

(EAN: 9781904933052)