Caister Academic Press

Burkholderia: Molecular Microbiology and Genomics

Publisher: Horizon Bioscience
Editor: Tom Coenye and Peter Vandamme Universiteit Gent, B-9000 Gent, Belgium
Publication date: January 2007
ISBN: 978-1-904933-28-1 (hardback)
ISBN: 978-1-904933-41-0 (ebook)
Pages: x + 304

Members of the genus Burkholderia are a fascinating group of bacteria exhibiting immense ecological and metabolic diversity. Their notoriety as pathogens, including that of potential biological weapons, is ironically matched by their value as biopesticides and bioremediators. For example, B. cepacia complex organisms can reduce an onion bulb to a macerated pulp, protect other crops from bacterial and fungal disease, "clean up" aquifers and soils contaminated by recalcitrant herbicides, colonise the lungs of people with cystic fibrosis and, if this diversity is not striking enough, are not only innately resistant to most major groups of antibiotics, but can use that most famous of antimicrobials, penicillin G, as a nutrient! This amazing versatility has attracted huge scientific interest in recent years and given that nine completed and seventeen draft Burkholderia genome sequences now available, the point has been reached where there is an urgent need to summarise and review the molecular biology, genomics, biochemistry, pathogenesis and beneficial properties of these important organisms.

This volume brings together the expertise and enthusiasm of an international panel of leading Burkholderia researchers to provide a state-of-the art overview of these important organisms. Topics covered include epidemiology, comparative genomics, antibiotic resistance, polysaccharides, beneficial interaction with plants, and much more. Each chapter is independent and can be read in isolation, but as a whole the book provides an important resource summarising our current knowledge of Burkholderia molecular biology and genomics.

Essential reading for all researchers working with Burkholderia and related organisms, and recommended reading for other scientists working bacterial genomics, antibacterial research, bacterial molecular and cellular biology, environmental microbiology, and bioremediation.

Chapter List:

John R. W. Govan

Chapter 1: Diversity and Role of Burkholderia spp.
Peter Vandamme, John Govan and John LiPuma

Chapter 2: Epidemiology, Typing and Population Genetics of Burkholderia Species
Tom Coenye and John J. LiPuma

Chapter 3: Comparative Genomics of Burkholderia Species
Eshwar Mahenthiralingam and Pavel Drevinek

Chapter 4: Antibiotic Resistance of Burkholderia spp.
Jane L. Burns

Chapter 5: Polysaccharides of Burkholderia spp.
Joanna B. Goldberg

Chapter 6: Interaction of Burkholderia Species With the Phagocytic System
Kelly L. MacDonald and David P. Speert

Chapter 7: Beneficial Interactions of Burkholderia spp. With Plants
Jacques Balandreau and Patrick Mavingui

Chapter 8: The Phytopathogenic Burkholderia
Carlos F. Gonzalez, Vittorio Venturi and Amanda S. Engledow

Chapter 9: Biodegradation of Organic Anthropogenic Pollutants by Burkholderia Species
Vincent J. Denef

Chapter 10: Molecular Mechanisms of Virulence of Burkholderia pseudomallei and Burkholderia mallei
Donald E. Woods

Chapter 11: Model Systems of Burkholderia cepacia Complex Infection
Pamela A. Sokol

Chapter 12: Social Behaviour of Members of the Genus Burkholderia: Quorum Sensing and Biofilms
Kathrin Riedel and Leo Eberl

Chapter 13: Intracellular Survival of Burkholderia cepacia Complex Isolates
Miguel A. Valvano, Kendra E. Maloney, Julie Lamothe, and Soledad Saldías

(EAN: 9781904933281)