Caister Academic Press

Biodefense: Principles and Pathogens

Publisher: Horizon Bioscience
Editors: Michael S. Bronze and Ronald A. Greenfield College of Medicine, University of Oklahoma Health Sciences Center and Oklahoma City VA Medical Center, Oklahoma City, OK 73190, USA
Publication date: April 2005
ISBN-10: 1-904933-12-2
ISBN-13: 978-1-904933-12-0
Pages: x + 838

How to Order

The antrax attacks by bioterrorists in the USA in October 2001 served to highlight our vunerability to biological warfare and to act as an impetus for a massive increase in funding for biodefense research. In this timely book, top biodefense experts critically review every aspect of this complex issue. The microbiology, diagnosis, pathogenesis, epidemiology, infection control and novel therapeutics for all the key pathogens involved are comprehensively covered. Biodefense is currently focused on anthrax, smallpox, plague, tularemia, botulism and viral hemorrhagic fevers and entire chapters are devoted to each of these topics. Further chapters cover the bioterrorism threat from other diseases including brucellosis, glanders, melioidosis, psittacosis, Q fever, typhoid, gastroenteritis and cryptosporidiosis. Biological toxins derived from living organisms, such as the epsilon toxin derived from Clostridium perfringens, mycotoxins and plant-derived toxins such as ricin are also reviewed in detail. Two fascinating chapters are devoted to agroterrorism, the use of infectious agents that target animals and plants to decimate the food supply. Additional chapters cover emerging pathogens and novel bio-engineered agents that could be used in bioterrorism. The book also covers hospital preparedness, infection control, psychosocial issues, and the evolving methods for surveillance and detection in biodefence.

Essential reading for everyone with an interest in biodefense, microbial pathogenesis, microbial genomics, antimicrobials, biotechnology, and recommended reading for students and health professionals.


"... this book is an encyclopaedic source of valid data that should not be lacking from the book collections of hospitals, general practitioners and all other with a professional (or national defence) interest in infectious diseases and their complications." from FEMS Immunology and Medical Microbiology (2005) 45: 351352.

" ... takes an extremely broad view of the threat ... if the reader is interested in delving beyond the CDC Category A list, this book can provide examples of B and even C Category organisms (and) moves beyond the standard BW threat chapters into related issues such as psychosocial consequences of an attack." from Microbiology Today (2005) August issue.

"The book serves as an invaluable planning tool for public health initiatives in major incident management. The sections on public health preparedness, hospital preparedness and surveillance and detection and psychosocial issues in bioterrorism will be of interest to anyone working in emergency and disaster planning." from Eastern Mediterranean Health Journal (2005).

"a good primer on current issues in biodefense ... a nice addition to any biodefense, infectious disease, or biological safety library." from Applied Biosafety (2005) 10(4): 266-267.

"... the book provides practical information ... adds a unique state and local perspective on planning ... to prepare for a biological attack." from Doody's (2006).

"... a remarkable and comprehensive overview of a wide number of biodefense issues of potential interest to a variety of readers." from Clin. Infect. Dis. (2006) 42: 735.

Chapter List:

Part I: General Issues in Biopreparedness

Chapter 1
Michael S. Bronze and Ronald A. Greenfield

Chapter 2
History of Biological Weapons Development and Deployment
R. Richard Hamerla

Chapter 3
Public Health Preparedness
R. Gregory Evans and Bruce W. Clements

Chapter 4
Public Policy and Legal Issues Surrounding Terrorism and Preparedness in the United States
Kenneth J. Levit and Peter P. Budetti

Chapter 5
Hospital Preparedness and Infection Control
A. Rekha K. Murthy and Matthew Bidwell Goetz

Chapter 6
Surveillance and Detection for Bioterrorism: Traditional and Evolving Methods
Kristy K. Bradley, Kenneth D. Clinkenbeard, J. Michael Crutcher, and Rebecca J. Morton

Chapter 7
Psychosocial Issues in Bioterrorism
Betty Pfefferbaum, Carol S. North, and Rose L. Pfefferbaum

Part II: Diseases Potentially Resulting From an Attack Deploying Agents or Toxins Against Humans

Section 1: United States Centers for Disease Control and Prevention (CDC) Category A Diseases

Chapter 8
Ronald A. Greenfield, Hélène Carabin, Douglas A. Drevets, and Michael S. Gilmore

Chapter 9
Ronald A. Greenfield, Leonard N. Slater, and Michael S. Bronze

Chapter 10
Douglas A. Drevets

Chapter 11
Steven H. Nazarian, Grant McFadden, and Mark M. Huycke

Chapter 12
Linda J. Machado, Hélène Carabin, and Darrin R. Akins

Chapter 13
Viral Hemorrhagic Fevers
Michael S. Bronze, Hélène Carabin, and Siddhartha Mahanty

Section 2: CDC Category B Diseases

Chapter 14
Other Biological and Microbiological Toxins: Staphylococcal Enterotoxin B, Epsilon Toxin of Clostridium perfringens, Ricin, and Mycotoxins
Malak Kotb and Michael S. Bronze

Chapter 15
Diseases Due to other Category B Bacterial Pathogens I: Brucellosis, Glanders, and Melioidosis
Gene W. Voskuhl, Ronald A. Greenfield, and Michael S. Bronze

Chapter 16
Diseases Due to Other Category B Bacterial Pathogens II: Psittacosis, Q Fever, and Typhus
Karen A. Wendel

Chapter 17
Bioterrorism and Threats to Food Safety: Campylobacter, Salmonella, Shigella, diarrheagenic Escherichia coli, and Listeria
James M. Fleckenstein and Seema K. Patel

Chapter 18
Bioterrorism and Threats to Water Safety: Cholera and Cryptosporidiosis
Daniel T. Boatright and Ronald A. Greenfield

Chapter 19
Encephalitis Viruses as Potential Agents of Bioterrorism
Michael S. Bronze, John D. Morrey, Pand Aaron Olsen

Section 3. CDC Category C Diseases

Chapter 20
Emerging Infectious Diseases
Shu-Hua Wang, Fred A. Lopez and Charles V. Sanders

Chapter 21
Miscellaneous Threats:Highly Pathogenic Avian Influenza and Novel Bio-engineered Organisms
Daniel R. Perez, Steven H. Nazarian, Grant McFadden and Michael S. Gilmore

Part III: Agroterrorism

Chapter 22
Animal Diseases as a Possible Consequence of Biological Attack
Hélène Carabin, Daniel Perez, Johnnie Lee Gilpen and Ronald A. Greenfield

Chapter 23
Plant Diseases as a Possible Consequence of biological attack
Forrest W. Nutter and Lawrence V. Madden

How to buy this book

(EAN: 9781904933120)