The Bacterial Phosphotransferase System
Publisher: Horizon Scientific Press
Editor: Milton H. Saier Jr. University of California at San Diego, La Jolla CA 92093-0116,USA
Publication date: March 2002
ISBN-10: 1-898486-35-2 (hbk)
ISBN-13: 978-1-898486-35-0 (hbk)
Pages: x + 291
Following it's discovery in E.coli by Kundig, Ghosh and Rosema thirty seven years ago, a wealth of information has accumulated on the bacterial Phosphotransferase system (PTS). Since then the PTS has been found in a wide variety of different bacteria where it has been recognised to play a pivotal role in numerious aspects of bacterial cellular physiology. While the primary functions of this system involve sugar reception, transport and phosphorylation, the secondary functions include the regulation, both directly and indirectly, of important metabolic pathways. In this book, internationally recognised authors review the current research on the PTS, discuss the multifaceted structural and functional aspects of the system and attempt to provide a realistic forecast of future discoveries. Study of this important system will contribute to our understanding of prokaryotic physiology and pathogenesis, will allow major advances in biotechnology, and will result in the development of agents capable of effectively combating harmful microorganisms.
Chapter List
Chapter1
The Bacterial Phosphotransferase System: Structure, Function, Regulation and Evolution
Milton H. Saier, Jr.
Chapter 2
The Complete Phosphotransferase System in Escherichia coli
Jason H. Tchieu, Vic Norris, Jeremy S. Edwards, and Milton H. Saier, Jr.
Chapter 3
Three-Dimensional Structures of Protein-Protein Complexesin the E. coli PTS
Alan Peterkofsky, Guangshun Wang, Daniel S. Garrett, Byeong Ryong Lee, Yeong-Jae Seok, and G. Marius Clore
Chapter 4
Routes for Fructose Utilization by Escherichia coli
Hans L. Kornberg
Chapter 5
Facilitation of Bacteriophage Lambda DNA Injection by Inner Membrane Proteins of the Bacterial Phosphoenol-pyruvate:Carbohydrate Phosphotransferase System (PTS)
Margarita Esquinas-Rychen and Bernhard Erni
Chapter 6
Regulation of PTS Gene Expression by the Homologous Transcriptional Regulators, Mlc and NagC, in Escherichia coli (or How Two Similar Repressors Can Behave Differently)
Jacqueline Plumbridge
Chapter 7
Regulation of Galactoside Transport by the PTS
Masayuki Kuroda, Thomas H. Wilson, and Tomofusa Tsuchiya
Chapter 8
Regulation of E. coli Glycogen Phosphorylase Activity by HPr
Yeong-Jae Seok, Byoung-Mo Koo, Melissa Sondej, and Alan Peterkofsky
Chapter 9
Use of Staphylococcus aureus 6-P-b-Galactosidase and GFP as Fusion Partners for Lactose-Specific IIC Domain from Staphylococcus aureus
Claudia M. Kowolik and Wolfgang Hengstenberg
Chapter 10
Hierarchical Control versus Autoregulation of Carbohydrate Utilization in Bacteria
M. G. W. Gunnewijk, P. T. C. van den Bogaard, L.M. Veenhoff, E.H. Heuberger, W. M. de Vos, M. Kleerebezem, O. P. Kuipers and B. Poolman
Chapter 11
Corynebacterium diphtheriae: a PTS View to the Genome
Stephan Parche, Andreas W. Thomae, Maximilian Schlicht, and Fritz Titgemeyer
Chapter 12
Corynebacterium glutamicum: a Dissection of the PTS
Stephan Parche, Andreas Burkovski, Georg A. Sprenger, Brita Weil, Reinhard Krämer, and Fritz Titgemeyer
Chapter 13
Evidence for a Dimerisation State of the Bacillus subtilis Catabolite Repression HPr-Like Protein, Crh
François Penin, Adrien Favier, Roland Montserret, Bernhard Brutscher, Josef Deutscher, Dominique Marion and Anne Galinier
Chapter 14
Catabolite Regulation of the Cytochrome c550-Encoding Bacillus subtilis cccA Gene
Vicente Monedero Grégory Boël and Josef Deutscher
Chapter 15
Phosphotransfer Functions of Mutated Bacillus subtilis HPr-Like Protein Crh Carrying a Histidine in the Active Site
Emmanuelle Darbon, Anne Galinier, Dominique Le Coq, and Josef Deutscher
(EAN: 9781898486350)
