Published: 2010 ISBN: 978-1-904455-73-8
Price: GB £159 or US $310
Cutting-edge topics in Salmonella genomics and molecular biology and a timely snapshot of the current state of research. Topics include latest approaches to sub-species level classification and phage typing of Salmonella, comparative genomics, genetic determinants for survival in different environments and the evolution of niche specialization. The book also explores the latest genomic information and molecular characterizations of sRNAs, fimbriae, flagella and secreted virulence factors. Moreover, S. Typhi pathogenesis, interactions of the host with intracellular Salmonella and the host\'s anti-Salmonella immune response are reviewed. The current knowledge on Salmonella biofilm formation and a progress report on using Salmonella as an anti-tumour tool conclude this compendium. read more ...
Published: 2010 ISBN: 978-1-904455-71-4
Price: GB £159 or US $310
Written by internationally renowned insect virologists, chapters review the current molecular biology of all the major groups of insect pathogenic viruses and suggest future directions for research. The book is divided into three parts: 1) DNA viruses 2) RNA viruses and 3) current hot-topics in insect virology. Virus groups covered include: Ascoviruses, Baculoviruses, Densoviruses, Entomopoxviruses, Hytrosaviruses, Iridoviruses, Nudiviruses, Polydnaviruses, Dicistroviruses, Iflaviruses, Nodaviruses, Tetraviruses and Cypoviruses. The special topics chapters review exciting recent developments in insect virology including RNAi, insect antiviral responses, structural comparison of insect RNA viruses, and viral ecology. read more ...
Published: 2010 ISBN: 978-1-904455-70-7
Price: GB £159 or US $310
With contributions from a broad range of leading researchers this book focuses on current technology and its applications. Although aimed primarily at research scientists and graduate students in water microbiology, the topics and techniques are equally applicable to all branches of environmental microbiology. The initial chapters cover the concentration, detection and characterization of microbes in drinking water, other chapters are technology focused and cover topics such as geochips and microarrays and their applications, Raman microspectroscopy and related single cell techniques, the use of amoebae hosts, bacteria and bacteriophage as bioreporters, viability of detected microbes and fecal source tracking. read more ...
Published: 2010 ISBN: 978-1-904455-69-1
Price: GB £159 or US $310
An international team of experts reviews a selection of important model systems, providing a timely snapshot of the current state of research in the field. The book opens with an introductory chapter that reviews the diversity of signal recognition mechanisms, illustrating the breadth of the field. Subsequent chapters include descriptions of the sensing of ligands (α-ketoglutarate, adenylate energy charge, glutamine and xenobiotic compounds), chemoreceptors, iron-sulfur cluster-based sensors, metal-dependent and metal-responsive sensors, thiol-based sensors, and PDZ domains as sensors of other proteins. This book provides essential reading for everyone with an interest in sensory mechanisms, regulatory networks and responses to environmental stress in bacteria. read more ...
Published: 2010 ISBN: 978-1-904455-68-4
Price: GB £159 or US $310
This book brings together the expertise and enthusiasm of the leading bifidobacteria experts from around the world to provide a state-of-the art overview of the molecular biology and genomics of this exciting and important microbial genus. Topics include: ecology, genomics, comparative genomics, metabolism, acid and bile resistance, stress response, probiotic properties, antimicrobial activity, interaction with the intestinal mucosa, safety assessment of bifidobacteria, synthesis and utilization of exopolysaccharides and prebiotics, antibiotic resistance/susceptibility profiles, viability and stability in commercial preparations, mobile genetic elements, cloning vectors and genetic manipulation of bifidobacteria. Essential reading for every bifidobacteria researcher, from the PhD student to the experienced scientist, and recommended reading for everyone with an interest in probiotics. read more ...
Published: 2010 ISBN: 978-1-904455-67-7
Price: GB £159 or US $310
An ideal introduction to molecular phylogeny for all microbiologists and an essential review of current concepts for experts in the field. The expert authors describe current concepts in molecular phylogeny and their application with respect to microorganisms. Topics include a historical overview, computational tools, multilocus sequence analysis, 16S rRNA phylogenetic trees, rooting of the universal tree of life, applications of conserved indels, lateral gene transfer, endosymbiosis and the evolution of plastids. read more ...
Published: 2010 ISBN: 978-1-904455-66-0
Price: GB £159 or US $310
This timely volume reviews the current state-of-the-art research and development of different nanomaterials (nanostructured catalytic membranes, nanosorbents, nanocatalysts and bioactive nanoparticles) and their application in water treatment, purification and disinfection. The expert authors have contributed chapters focusing on the cutting-edge research in this emerging technology and its applications in microbiology and water treatment. read more ...
Published: 2010 ISBN: 978-1-904455-65-3
Price: GB £159 or US $310
An international team of authors presents a comprehensive collection of reviews on iron uptake and metabolism in various microorganisms including Rhizobia, Bordetella, Shigella, E. coli, Erwinia, Vibrio, Aeromonas, Francisella, Bacteroides, Campylobacter, Cyanobacteria, Bacillus, Staphylococci and yeasts. An entire chapter is dedicated to siderophores and another to heme uptake. The volume provides an expert and timely summary of current knowledge, with a focus on molecular and genetic aspects, and highlights some of the most exciting recent developments. read more ...
Published: 2010 ISBN: 978-1-904455-63-9
Price: GB £159 or US $310
A panel of experts distil the most important up-to-date research findings in their respective calicivirus field of study producing timely and comprehensive reviews. Each chapter gives the reader a brief introduction to the topic followed by a descriptive discussion of the past and present research areas. Topics include: norovirus epidemiology; calicivirus contamination of the environment; genome organization and recombination, proteolytic cleavage and viral proteins; viral protein structures; virus-host interactions; calicivirus reverse genetics and replicon systems; feline calicivirus; swine calicivirus; murine norovirus pathogenesis and immunity; murine norovirus translation, replication and reverse genetics; and lagoviruses. read more ...
Published: 2010 ISBN: 978-1-904455-62-2
Price: GB £159 or US $310
Expert EBV virologists comprehensively review this important subject from a genetic, biochemical, immunological, and cell biological perspective. Topics include: latent infections, EBV leader protein, EBNA-1 in viral DNA replication and persistence, EBNA-2 in transcription activation of viral and cellular genes, the nuclear antigen family 3 in regulation of cellular processes, molecular profiles of EBV latently infected cells, latent membrane protein 1 oncoprotein, regulation of latency by LMP2A, role of noncoding RNAs in EBV-induced cell growth and transformation and the regulation of EBV latency by viral lytic proteins. Essential reading for all EBV virologists as well as clinical and basic scientists working on oncogenic viruses. read more ...
Published: 2010 ISBN: 978-1-904455-61-5
Price: GB £159 or US $310
Internationally acclaimed researchers critically review the most important aspects of research on anaerobic parasitic protozoa, providing the first coherent picture of their genomics and molecular biology since the publication of the genomes. Chapters are written from a molecular and genomic perspective and contain speculative models upon which future research efforts can be based. Topics include: the genomes of Entamoeba histolytica, Trichomonas vaginalis, Giardia and other diplomonads; the cytoskeletons of Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis; genomic analyses and manipulation of gene expression in Entamoeba histolytica; nuclear and chromosomal structure and replication in Giardia ; and the mitochondrion-like organelles of a fourth anaerobe, Blastocystis. Essential reading for all researchers working with these protozoa and related organisms and with eukaryotic model organisms. Recommended text for all parasitology laboratories. read more ...
Published: 2010 ISBN: 978-1-904455-60-8
Price: GB £159 or US $310
In this timely book, top lentivirus and macrophage specialists comprehensively review cutting-edge topics in the molecular and cellular biology of the lentivirus-macrophage interaction. Topics include: lentivirus tropism and disease, macrophage biology, macrophage in HIV-1 infection and disease progression, post-entry restrictions to lentiviral replication, HIV-2 tropism and disease, SHIV model of disease, the felid immunodeficiency viruses, EIAV, small ruminant lentiviruses, bovine lentiviruses, coinfections and superinfections. Essential reading for every lentivirologist and retrovirologist, this is also a recommended text for all virology, immunology and molecular biology laboratories. read more ...
Published: 2010 ISBN: 978-1-904455-59-2
Price: GB £159 or US $310
Major current advances in microbial population genetics and genomics. Fundamental concepts, genetic tools and comprehensive reviews of recent data from SNP surveys, whole-genome DNA sequences and microarray hybridizations. Covers broad groups of microorganisms including viruses, bacteria, archaea, fungi, protozoa and algae. A major focus is the application of molecular tools in the study of genetic variation. Topics include microbial systematics, comparative microbial genomics, horizontal gene transfer, pathogenic bacteria, nitrogen-fixing bacteria, cyanobacteria, microalgae, fungi, malaria parasites, viral pathogens and metagenomics. Essential book for everyone involved in population genetics and highly recommended reading for all microbiologists. read more ...
Published: 2010 ISBN: 978-1-904455-58-5
Price: GB £159 or US $310
A comprehensive guide to Borrelia providing an encyclopedic overview of the molecular biology of this important genus and the pathogenesis of the diseases caused. Leading authorities have contributed chapters on topics such as Borrelia genomics, DNA replication, gene regulation, transcriptomics, proteomics, metabolism and physiology, cellular structure, motility and chemotaxis, genetic manipulation, evolutionary genetics, ecology, tick interactions, Lyme disease and relapsing fever pathogenesis, animal models, host response, detection, and vaccines. The volume is essential for anyone involved in Borrelia research and is strongly recommended for microbiologists, immunologists, and physicians involved in spirochete research, Lyme borreliosis, or relapsing fever. The book is a recommended reference volume for all microbiology libraries. read more ...
Published: 2010 ISBN: 978-1-904455-57-8
Price: GB £159 or US $310
Critically reviews the current research and the most important discoveries in this highly topical field. Subjects covered include the NS1 protein of influenza A virus, the structure of influenza NS1, influenza B hemagglutinin, influenza A nucleoprotein, influenza A hemagglutinin glycoproteins, the M2 channel, virulence genes of the 1918 H1N1 influenza, influenza virus polymerase, gene diagnostic microarrays, and computer-assisted vaccine design. read more ...
Published: 2010 ISBN: 978-1-904455-56-1
Price: GB £159 or US $310
A comprehensive review of the RNAi area from international specialists. Major themes of the book include the latest findings on RNAi-virus interactions and progress in the development of RNAi-based antiviral therapeutics. Topics include the role of RNAi in natural antiviral defense mechanisms, the improvement of the efficacy and safety of RNAi-based antiviral drugs, and the development of RNAi as a new therapeutic tool for fighting specific viruses, including HIV, HCV and respiratory viruses. Also outlined are new avenues for research thus providing a stimulus for further investigation. Essential reading for researchers involved in RNAi or antiviral research and a recommended text for all virology laboratories. read more ...
Published: 2010 ISBN: 978-1-904455-55-4
Price: GB £159 or US $310
Written by the top retroviral specialists, this book reviews the genomics, molecular biology, and pathogenesis of these important viruses, comprehensively covering all the recent advances. Topics include: host and retroelement interactions, endogenous retroviruses, retroviral proteins and genomes, viral entry and uncoating, reverse transcription and integration, transcription, splicing and RNA transport, pathogenesis of oncoviral infections, pathogenesis of immunodeficiency virus infections, retroviral restriction factors molecular vaccines and correlates of protection, gammaretroviral and lentiviral vectors, non-primate mammalian and fish retroviruses, simian exogenous retroviruses, and HTLV and HIV. read more ...
Published: 2010 ISBN: 978-1-904455-54-7
Price: GB £159 or US $310
The diverse and multiple aspects of metagenomics and the multiplicity of its potential applications. The new theoretical insights, the more recent applications, and the dynamically developing methods of data acquisition and analysis. read more ...
Published: 2010 ISBN: 978-1-904455-53-0
Price: GB £159 or US $310
In this book leading Aspergillus researchers review and summarise the most important aspects of Aspergillus molecular biology and genomics. The book opens with a fascinating overview of the genus Aspergillus. This is followed by in-depth reviews of the Aspergillus molecular systematics, comparative genomics, bioinformatics and systems biology of Aspergillus, transcriptional regulation, genetics and genomics of sexual development of A. nidulans, genomics and secondary metabolism, ecology, development and gene regulation in A. flavus, functional systems biology, and novel industrial applications of A. oryzae genomics. Essential reading for everyone with an interest in Aspergillus and related fungi. read more ...
Published: 2010 ISBN: 978-1-904455-52-3
Price: GB £159 or US $310
The current state-of-the-art of environmental microbiology with an emphasis on molecular biology and genomics. A range of technologies and their applications in environmental microbiology. The book focuses on the microbial diversity and phylogeny of microorganisms in the environment and describes the molecular toolbox currently available for the study of the composition and diversity of microbial communities and their functions. Also covers the application of these approaches in various environments including soil, marine water, plants, humans and wastewater treatment. read more ...
Published: 2010 ISBN: 978-1-904455-51-6
Price: GB £150 or US $310
The latest theory and clinical significance of molecular mechanisms in meningococcal disease. Leading authorities have contributed chapters on topics such as gene expression, genomics, biofilms, denitrification, adhesion strategies, mechanisms of cellular invasion, inate immunity, complement, apoptosis, acquired immunity, vaccine development, epidemiology and antibiotic resistance. read more ...
Published: 2010 ISBN: 978-1-904455-50-9
Price: GB £150 or US $310
Topics include: evolutionary history, epidemiology, translation and processing of the viral polyprotein, viral replication, the role of the viral untranslated regions, pathogenesis, host response to DENV, development of animal models, DENV-mosquito interactions, dynamics of dengue virus transmission, emergence of DENV from its ancestral, sylvatic cycle, vaccines, novel anti-dengue drugs, and passive immunotherapy. Essential reading for every dengue virologist and highly recommended for all flavivirus and arbovirus virologists. read more ...
Published: 2009 ISBN: 978-1-904455-49-3
Price: GB £150 or US $310
A skillful selection of topics and a panel of acknowledged experts as authors ensure that this concise volume will be of exceptional importance to everyone involved in DNA superfamily research as well as scientists interested in microbial physiology and multidrug resistance. read more ...
Published: 2009 ISBN: 978-1-904455-48-6
Price: GB £150 or US $310
The current knowledge and latest research on prokaryotic pili and flagella. The emphasis is on the molecular biology, genetics, structure, assembly and function of these structures. read more ...
Published: 2009 ISBN: 978-1-904455-47-9
Price: GB £150 or US $310
Applications of lab-on-a-chip devices in biotechnology, medicine, clinical diagnostics, chemical engineering, and pharmaceutics. Various electrophoresis and liquid chromatography applications, methods for cell separation, blood cell separation, clinical applications, protein, genetic, PCR, transcriptome analysis, cell manipulation and analysis, cell viability analysis, microorganism capturing. read more ...
Published: 2009 ISBN: 978-1-904455-46-2
Price: GB £150 or US $310
Current lab-on-a-chip technologies including theoretical and technical information for the understanding of the technology and the reproduction of experiments. Will help the understanding of current LOC technologies, performance of similar experiments, the design of new LOC systems and development of new methodologies and applications. read more ...
Published: 2009 ISBN: 978-1-904455-45-5
Price: GB £150 or US $310
In this timely book a cohort of experienced and authoritative experts review the most important innovations in research on and biotechnological applications of bacterial polysaccharides. The book takes an interdisciplinary view that examines this fascinating subject area in detail from molecular biology, genome-, transcriptome- and proteome-wide perspectives, and looks at the ecological aspects and systems biology approaches. Hence the book provides a sound basis for future research directions including high efficiency applications of bacterial polysaccharides in medicine, the food industry, and renewable energy production. read more ...
Published: 2009 ISBN: 978-1-904455-44-8
Price: GB £150 or US $310
This timely volume serves as an update on the most important microbial toxins. Written by internationally respected scientists, topics reviewed include: toxins carried by mobile genetic elements, botulinum neurotoxins, anthrax, subtilase cytotoxin, Pasteurella multocida toxin, RTX toxins of vibrios, vacA toxin, staphylococcal immune evasion toxins and fungal ribotoxins. read more ...
Published: 2009 ISBN: 978-1-904455-43-1
Price: GB £150 or US $310
Everything that is known about Acanthamoeba is critically reviewed and divided into easy-to-follow sections. The current state of research on genomics, molecular and cellular biology, life cycles, geographical distribution, role in ecosystem, morphology, motility, phylogenetics, genotyping, metabolism, regulation of morphogenesis, host-parasite interactions, the molecular and immunological basis of pathogenesis, methods of transmission, epidemiology, clinical manifestation, diagnosis, treatment, new target development and drug resistance, and much more. read more ...
Published: 2009 ISBN: 978-1-904455-42-4
Price: GB £150 or US $310
A broad and in-depth description of the current knowledge of bacterial protein secretion and its role in pathogenesis. This publication on bacterial secreted proteins, the secretory systems of bacteria and the vital role of secreted proteins in bacterial pathogenesis is aimed at microbiologists, molecular biologists, public health scientists and researchers engaged in the study of pathogenesis, drug design and vaccine development. read more ...
Published: 2009 ISBN: 978-1-904455-41-7
Price: GB £150 or US $310
A major new reference for all dairy technologists, microbiologists and biotechnologists in the academic and industrial sectors. Written by an international team of scientists the volume focuses on recent research on the molecular biology and genomics of Lactobacillus. Topics covered include phylogenetics, taxonomy, comparative genomics, functional genomics, the intestinal microflora, surface proteins, stress responses, interaction with the immune system, probiotics, anti-cancer potential, and much more. Essential reading for all scientists involved with lactic acid bacteria or probiotic research and a recommended book for all microbiology laboratories. read more ...
Published: 2009 ISBN: 978-1-904455-40-0
Price: GB £150 or US $310
A critical review of the current and most recent advances in the genomics and molecular biology of mycobacteria. Focuses on the topical and most relevant aspects. Includes strain variation and evolution, hypervirulent strains, electron transport and respiration, lipid biosynthesis, DNA repair, oxygen signaling, sulphur metabolism, protein secretion, the protein kinase family. read more ...
Published: 2009 ISBN: 978-1-904455-39-4
Price: GB £150 or US $310
A comprehensive guide to the most up-to-date real-time PCR technology and applications. The latest PCR platforms, fluorescent chemistries, validation software, data analysis, internal and external controls,clinical diagnostics, biodefense, RNA expression studies, validation of array data, mutation detection, food authenticity and legislation, NASBA, molecular halotyping. read more ...
Published: 2009 ISBN: 978-1-904455-38-7
Price: GB £150 or US $310
In this book internationally recognised Clostridium experts critically review the most important aspects of clostridial research, providing the first coherent picture of the organism's molecular and cellular biology in this post-genomic era. The first major focus of the book is the genetics and molecular biology of the major clostridial toxins including: botulinum and tetanus neurotoxins, C. difficile large exotoxins, C. perfringens enterotoxin, pore-forming and binary bacterial toxins. Other topics include: molecular epidemiology of C. botulinum and C. difficile, metabolic networks in C. acetobutylicum, development of genetic knock-out systems for clostridia, surface structures, anti tumor potential of clostridia, and antibiotic resistance determinants in C. difficile. read more ...
Published: 2009 ISBN: 978-1-904455-37-0
Price: GB £150 or US $310
In this book, internationally acclaimed experts review the most important developments providing an invaluable, up-to-date summary of the molecular biology and genomics of plant pathogenic bacteria. The book opens with two chapters on bacterial evolution, diversity and taxonomy, topics that have been transformed by molecular biology and genomics analyses. The third chapter delves into the crucially understudied area of pathogen adaptation to the plant apoplast environment. The following seven chapters focus on specific plant pathogens: Agrobacterium, Leifsonia, Pectobacterium, Pseudomonas, Ralstonia, Xanthomonas, and Xylella. The next four chapters review specific, intensively studied areas of research in the plant pathogen field: microbe associated molecular patterns (MAMPs) and innate immunity; use of bacterial virulence factors to suppress plant defence; cyclic di-GMP signalling and the regulation of virulence; and plasmids and the spread of virulence. The final chapter covers the critical area of bioinformatics. read more ...
Published: 2009 ISBN: 978-1-904455-36-3
Price: GB £150 or US $310
Describes in detail the use of microorganisms for the production of the most important biopolymers and polymer precursors. The authors describe, in depth, the biosynthetic pathways, physical properties and industrial production processes and discuss in detail the genetic and metabolic engineering of microorganisms for biopolymer production. Also highlighted are the applications and potential applications of the biopolymers and microbial biotechnology read more ...
Published: 2008 ISBN: 978-1-904455-35-6
Price: GB £150 or US $310
Written by acknowledged experts in the field, this volume provides an up to date treatment of the structure, function and application of plasmids with a particular emphasis on current and future trends. The book is aimed primarily at research scientists, graduate students and professional scientists but will also be of great interest to all molecular biologists and microbiologists involved in research or teaching. Chapters include a historical perspective on E. coli plasmids and the scientific background of the plasmids used routinely in laboratories to clone genes and to express proteins; an overview on the plasmids of archaea and eukarya; bioinformatic tools; horizontal gene transfer and the process of DNA transfer. Two entire chapters are devoted to the important medical applications of plasmids, including the correction of gene defects and vaccines to treat cancer or infectious diseases. read more ...
Published: 2008 ISBN: 978-1-904455-34-9
Price: GB £150 or US $310
Pasteurella book. In this timely book, leading international Pasteurellaceae scientists critically review the most important current research providing an up-to-date review of the molecular biology, genomics and virulence of these fascinating organisms. Topics covered include taxonomy and biodiversity, phylogeny, comparative genomics, competence, DNA uptake and transformation, proteomics and protein secretion, RTX toxins, lipopolysaccharides, biofilms, quorum sensing, antimicrobial resistance, diagnosis, and OMP and iron uptake. Each chapter is independent and can be read in isolation and as a whole the book provides an important resource summarising our current knowledge of Pasteurellaceae genomics and molecular biology. Essential reading for everyone working on Pasteurellaceae and related organisms. read more ...
Published: 2008 ISBN: 978-1-904455-33-2
Price: GB £150 or US $310
In this book leading V. cholerae experts, the chapters review the most important cutting-edge genetic facets of V. cholerae including its genomic organization, population genetics, molecular epidemiology, and synchronized regulation of gene expression. Other topics include the molecular basis for enhanced transmissibility of cholera during epidemics, survival of the pathogen in the environment, and above all the evolution of the species to attain increased fitness both as a pathogen and an environmental organism. Essential reading for everyone with an interest in Vibrio and recommended reading for other scientists working in microbial pathogenesis, microbial genomics and antimicrobial research. read more ...
Published: 2008 ISBN: 978-1-904455-32-5
Price: GB £150 or US $310
In this book a panel of expert international mycologists critically review the most important cutting-edge topics. Chapters are written from a molecular and genomic perspective and through the provision of extensive reference sections positively encourage readers to pursue the subject in greater detail. Topics include: gene expression and regulation, heterozygosity in Candida, molecular diagnosis, regulation of the host-fungal interaction, the development of anti-fungals, signal transduction, and mechanisms of multi-drug resistance. read more ...
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