Published: 2010 ISBN: 978-1-904455-56-1
Price: GB £159 or US $310
A comprehensive review of the RNAi area from international specialists. Major themes of the book include the latest findings on RNAi-virus interactions and progress in the development of RNAi-based antiviral therapeutics. Topics include the role of RNAi in natural antiviral defense mechanisms, the improvement of the efficacy and safety of RNAi-based antiviral drugs, and the development of RNAi as a new therapeutic tool for fighting specific viruses, including HIV, HCV and respiratory viruses. Also outlined are new avenues for research thus providing a stimulus for further investigation. Essential reading for researchers involved in RNAi or antiviral research and a recommended text for all virology laboratories. read more ...
Published: 2010 ISBN: 978-1-904455-55-4
Price: GB £159 or US $310
Written by the top retroviral specialists, this book reviews the genomics, molecular biology, and pathogenesis of these important viruses, comprehensively covering all the recent advances. Topics include: host and retroelement interactions, endogenous retroviruses, retroviral proteins and genomes, viral entry and uncoating, reverse transcription and integration, transcription, splicing and RNA transport, pathogenesis of oncoviral infections, pathogenesis of immunodeficiency virus infections, retroviral restriction factors molecular vaccines and correlates of protection, gammaretroviral and lentiviral vectors, non-primate mammalian and fish retroviruses, simian exogenous retroviruses, and HTLV and HIV. read more ...
Published: 2010 ISBN: 978-1-904455-54-7
Price: GB £159 or US $310
The diverse and multiple aspects of metagenomics and the multiplicity of its potential applications. The new theoretical insights, the more recent applications, and the dynamically developing methods of data acquisition and analysis. read more ...
Published: 2010 ISBN: 978-1-904455-53-0
Price: GB £159 or US $310
In this book leading Aspergillus researchers review and summarise the most important aspects of Aspergillus molecular biology and genomics. The book opens with a fascinating overview of the genus Aspergillus. This is followed by in-depth reviews of the Aspergillus molecular systematics, comparative genomics, bioinformatics and systems biology of Aspergillus, transcriptional regulation, genetics and genomics of sexual development of A. nidulans, genomics and secondary metabolism, ecology, development and gene regulation in A. flavus, functional systems biology, and novel industrial applications of A. oryzae genomics. Essential reading for everyone with an interest in Aspergillus and related fungi. read more ...
Published: 2010 ISBN: 978-1-904455-52-3
Price: GB £159 or US $310
The current state-of-the-art of environmental microbiology with an emphasis on molecular biology and genomics. A range of technologies and their applications in environmental microbiology. The book focuses on the microbial diversity and phylogeny of microorganisms in the environment and describes the molecular toolbox currently available for the study of the composition and diversity of microbial communities and their functions. Also covers the application of these approaches in various environments including soil, marine water, plants, humans and wastewater treatment. read more ...
Published: 2010 ISBN: 978-1-904455-51-6
Price: GB £150 or US $310
The latest theory and clinical significance of molecular mechanisms in meningococcal disease. Leading authorities have contributed chapters on topics such as gene expression, genomics, biofilms, denitrification, adhesion strategies, mechanisms of cellular invasion, inate immunity, complement, apoptosis, acquired immunity, vaccine development, epidemiology and antibiotic resistance. read more ...
Published: 2010 ISBN: 978-1-904455-50-9
Price: GB £150 or US $310
Topics include: evolutionary history, epidemiology, translation and processing of the viral polyprotein, viral replication, the role of the viral untranslated regions, pathogenesis, host response to DENV, development of animal models, DENV-mosquito interactions, dynamics of dengue virus transmission, emergence of DENV from its ancestral, sylvatic cycle, vaccines, novel anti-dengue drugs, and passive immunotherapy. Essential reading for every dengue virologist and highly recommended for all flavivirus and arbovirus virologists. read more ...
Published: 2009 ISBN: 978-1-904455-49-3
Price: GB £150 or US $310
A skillful selection of topics and a panel of acknowledged experts as authors ensure that this concise volume will be of exceptional importance to everyone involved in DNA superfamily research as well as scientists interested in microbial physiology and multidrug resistance. read more ...
Published: 2009 ISBN: 978-1-904455-48-6
Price: GB £150 or US $310
The current knowledge and latest research on prokaryotic pili and flagella. The emphasis is on the molecular biology, genetics, structure, assembly and function of these structures. read more ...
Published: 2009 ISBN: 978-1-904455-47-9
Price: GB £150 or US $310
Applications of lab-on-a-chip devices in biotechnology, medicine, clinical diagnostics, chemical engineering, and pharmaceutics. Various electrophoresis and liquid chromatography applications, methods for cell separation, blood cell separation, clinical applications, protein, genetic, PCR, transcriptome analysis, cell manipulation and analysis, cell viability analysis, microorganism capturing. read more ...
Published: 2009 ISBN: 978-1-904455-46-2
Price: GB £150 or US $310
Current lab-on-a-chip technologies including theoretical and technical information for the understanding of the technology and the reproduction of experiments. Will help the understanding of current LOC technologies, performance of similar experiments, the design of new LOC systems and development of new methodologies and applications. read more ...
Published: 2009 ISBN: 978-1-904455-45-5
Price: GB £150 or US $310
In this timely book a cohort of experienced and authoritative experts review the most important innovations in research on and biotechnological applications of bacterial polysaccharides. The book takes an interdisciplinary view that examines this fascinating subject area in detail from molecular biology, genome-, transcriptome- and proteome-wide perspectives, and looks at the ecological aspects and systems biology approaches. Hence the book provides a sound basis for future research directions including high efficiency applications of bacterial polysaccharides in medicine, the food industry, and renewable energy production. read more ...
Published: 2009 ISBN: 978-1-904455-44-8
Price: GB £150 or US $310
This timely volume serves as an update on the most important microbial toxins. Written by internationally respected scientists, topics reviewed include: toxins carried by mobile genetic elements, botulinum neurotoxins, anthrax, subtilase cytotoxin, Pasteurella multocida toxin, RTX toxins of vibrios, vacA toxin, staphylococcal immune evasion toxins and fungal ribotoxins. read more ...
Published: 2009 ISBN: 978-1-904455-43-1
Price: GB £150 or US $310
Everything that is known about Acanthamoeba is critically reviewed and divided into easy-to-follow sections. The current state of research on genomics, molecular and cellular biology, life cycles, geographical distribution, role in ecosystem, morphology, motility, phylogenetics, genotyping, metabolism, regulation of morphogenesis, host-parasite interactions, the molecular and immunological basis of pathogenesis, methods of transmission, epidemiology, clinical manifestation, diagnosis, treatment, new target development and drug resistance, and much more. read more ...
Published: 2009 ISBN: 978-1-904455-42-4
Price: GB £150 or US $310
A broad and in-depth description of the current knowledge of bacterial protein secretion and its role in pathogenesis. This publication on bacterial secreted proteins, the secretory systems of bacteria and the vital role of secreted proteins in bacterial pathogenesis is aimed at microbiologists, molecular biologists, public health scientists and researchers engaged in the study of pathogenesis, drug design and vaccine development. read more ...
Published: 2009 ISBN: 978-1-904455-41-7
Price: GB £150 or US $310
A major new reference for all dairy technologists, microbiologists and biotechnologists in the academic and industrial sectors. Written by an international team of scientists the volume focuses on recent research on the molecular biology and genomics of Lactobacillus. Topics covered include phylogenetics, taxonomy, comparative genomics, functional genomics, the intestinal microflora, surface proteins, stress responses, interaction with the immune system, probiotics, anti-cancer potential, and much more. Essential reading for all scientists involved with lactic acid bacteria or probiotic research and a recommended book for all microbiology laboratories. read more ...
Published: 2009 ISBN: 978-1-904455-40-0
Price: GB £150 or US $310
A critical review of the current and most recent advances in the genomics and molecular biology of mycobacteria. Focuses on the topical and most relevant aspects. Includes strain variation and evolution, hypervirulent strains, electron transport and respiration, lipid biosynthesis, DNA repair, oxygen signaling, sulphur metabolism, protein secretion, the protein kinase family. read more ...
Published: 2009 ISBN: 978-1-904455-39-4
Price: GB £150 or US $310
A comprehensive guide to the most up-to-date real-time PCR technology and applications. The latest PCR platforms, fluorescent chemistries, validation software, data analysis, internal and external controls,clinical diagnostics, biodefense, RNA expression studies, validation of array data, mutation detection, food authenticity and legislation, NASBA, molecular halotyping. read more ...
Published: 2009 ISBN: 978-1-904455-38-7
Price: GB £150 or US $310
In this book internationally recognised Clostridium experts critically review the most important aspects of clostridial research, providing the first coherent picture of the organism's molecular and cellular biology in this post-genomic era. The first major focus of the book is the genetics and molecular biology of the major clostridial toxins including: botulinum and tetanus neurotoxins, C. difficile large exotoxins, C. perfringens enterotoxin, pore-forming and binary bacterial toxins. Other topics include: molecular epidemiology of C. botulinum and C. difficile, metabolic networks in C. acetobutylicum, development of genetic knock-out systems for clostridia, surface structures, anti tumor potential of clostridia, and antibiotic resistance determinants in C. difficile. read more ...
Published: 2009 ISBN: 978-1-904455-37-0
Price: GB £150 or US $310
In this book, internationally acclaimed experts review the most important developments providing an invaluable, up-to-date summary of the molecular biology and genomics of plant pathogenic bacteria. The book opens with two chapters on bacterial evolution, diversity and taxonomy, topics that have been transformed by molecular biology and genomics analyses. The third chapter delves into the crucially understudied area of pathogen adaptation to the plant apoplast environment. The following seven chapters focus on specific plant pathogens: Agrobacterium, Leifsonia, Pectobacterium, Pseudomonas, Ralstonia, Xanthomonas, and Xylella. The next four chapters review specific, intensively studied areas of research in the plant pathogen field: microbe associated molecular patterns (MAMPs) and innate immunity; use of bacterial virulence factors to suppress plant defence; cyclic di-GMP signalling and the regulation of virulence; and plasmids and the spread of virulence. The final chapter covers the critical area of bioinformatics. read more ...
Published: 2009 ISBN: 978-1-904455-36-3
Price: GB £150 or US $310
Describes in detail the use of microorganisms for the production of the most important biopolymers and polymer precursors. The authors describe, in depth, the biosynthetic pathways, physical properties and industrial production processes and discuss in detail the genetic and metabolic engineering of microorganisms for biopolymer production. Also highlighted are the applications and potential applications of the biopolymers and microbial biotechnology read more ...
Published: 2008 ISBN: 978-1-904455-35-6
Price: GB £150 or US $310
Written by acknowledged experts in the field, this volume provides an up to date treatment of the structure, function and application of plasmids with a particular emphasis on current and future trends. The book is aimed primarily at research scientists, graduate students and professional scientists but will also be of great interest to all molecular biologists and microbiologists involved in research or teaching. Chapters include a historical perspective on E. coli plasmids and the scientific background of the plasmids used routinely in laboratories to clone genes and to express proteins; an overview on the plasmids of archaea and eukarya; bioinformatic tools; horizontal gene transfer and the process of DNA transfer. Two entire chapters are devoted to the important medical applications of plasmids, including the correction of gene defects and vaccines to treat cancer or infectious diseases. read more ...
Published: 2008 ISBN: 978-1-904455-34-9
Price: GB £150 or US $310
Pasteurella book. In this timely book, leading international Pasteurellaceae scientists critically review the most important current research providing an up-to-date review of the molecular biology, genomics and virulence of these fascinating organisms. Topics covered include taxonomy and biodiversity, phylogeny, comparative genomics, competence, DNA uptake and transformation, proteomics and protein secretion, RTX toxins, lipopolysaccharides, biofilms, quorum sensing, antimicrobial resistance, diagnosis, and OMP and iron uptake. Each chapter is independent and can be read in isolation and as a whole the book provides an important resource summarising our current knowledge of Pasteurellaceae genomics and molecular biology. Essential reading for everyone working on Pasteurellaceae and related organisms. read more ...
Published: 2008 ISBN: 978-1-904455-33-2
Price: GB £150 or US $310
In this book leading V. cholerae experts, the chapters review the most important cutting-edge genetic facets of V. cholerae including its genomic organization, population genetics, molecular epidemiology, and synchronized regulation of gene expression. Other topics include the molecular basis for enhanced transmissibility of cholera during epidemics, survival of the pathogen in the environment, and above all the evolution of the species to attain increased fitness both as a pathogen and an environmental organism. Essential reading for everyone with an interest in Vibrio and recommended reading for other scientists working in microbial pathogenesis, microbial genomics and antimicrobial research. read more ...
Published: 2008 ISBN: 978-1-904455-32-5
Price: GB £150 or US $310
In this book a panel of expert international mycologists critically review the most important cutting-edge topics. Chapters are written from a molecular and genomic perspective and through the provision of extensive reference sections positively encourage readers to pursue the subject in greater detail. Topics include: gene expression and regulation, heterozygosity in Candida, molecular diagnosis, regulation of the host-fungal interaction, the development of anti-fungals, signal transduction, and mechanisms of multi-drug resistance. read more ...
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